Optogenetic activation of serotonergic neurons changes masticatory movement in freely moving mice

Optogenetic activation of serotonergic neurons changes masticatory movement in freely moving mice

Abstract The serotonergic system modulates the neural circuits involved in jaw movement; however, the role of serotonin (5-HT) neurons in masticatory movement remains unclear. Here, we investigated the effect of selective activation of 5-HT neurons in the dorsal raphe nucleus (DRN), or the raphe obs...

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Bibliographic Details
Main Authors: Masanori Dantsuji, Ayako Mochizuki, Kiyomi Nakayama, Mitsuko Kanamaru, Masahiko Izumizaki, Kenji F. Tanaka, Tomio Inoue, Shiro Nakamura
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Mastication
Serotonin
Dorsal raphe
Channelrhodopsins
Optogenetics
Electromyography
Online Access:https://doi.org/10.1038/s41598-024-79429-5
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