Combined treatment for locally advanced cholangiocellular liver cancer - the case report

Liver resection is the standard in the treatment of patients with the local uncomplicated intrahepatic bile duct cancer. Systemic chemotherapy is prescribed in the presence of distant metastases. Difficulties in a choice of the treatment method come up when one or several factors are revealed: the t...

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Main Authors: A. N. Polyakov, Yu. I. Patyutko, A. Yu. Syskova, K. A. Romanova, I. S. Bazin, O. N. Sergeeva, E. R. Virshke, E. S. Makarov, E. Yu. Antonova, A. A. Kirshin, D. V. Podluzhnyi
Format: Article
Language:Russian
Published: QUASAR, LLC 2019-12-01
Series:Исследования и практика в медицине
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Online Access:https://www.rpmj.ru/rpmj/article/view/470
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author A. N. Polyakov
Yu. I. Patyutko
A. Yu. Syskova
K. A. Romanova
I. S. Bazin
O. N. Sergeeva
E. R. Virshke
E. S. Makarov
E. Yu. Antonova
A. A. Kirshin
D. V. Podluzhnyi
author_facet A. N. Polyakov
Yu. I. Patyutko
A. Yu. Syskova
K. A. Romanova
I. S. Bazin
O. N. Sergeeva
E. R. Virshke
E. S. Makarov
E. Yu. Antonova
A. A. Kirshin
D. V. Podluzhnyi
author_sort A. N. Polyakov
collection DOAJ
description Liver resection is the standard in the treatment of patients with the local uncomplicated intrahepatic bile duct cancer. Systemic chemotherapy is prescribed in the presence of distant metastases. Difficulties in a choice of the treatment method come up when one or several factors are revealed: the tumor spread towards the surrounding structures, multiple liver lesions, lymph nodes involvement signs. The complications presence manages treatment strategy too. The case describes the possibilities of an individual multimodal approach in a treatment strategy for the patient with locally advanced liver cholangiocarcinoma complicated by obstructive jaundice, cholangitis, cholangiogenic abscesses. The surgical approach was approved as the main one. Methods of interventional radiology, chemotherapy, radiation therapy were applied when necessary. The mentioned above treatment strategy allowed us to achieve good results in this difficult clinical case. The patient is alive for more than four years from the time of surgery, signs of progression are not currently defined.
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issn 2410-1893
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publisher QUASAR, LLC
record_format Article
series Исследования и практика в медицине
spelling doaj-art-80b3c75fee83463282bd986e3c617a2f2025-02-03T07:12:14ZrusQUASAR, LLCИсследования и практика в медицине2410-18932019-12-016415816710.17709/2409-2231-2019-6-4-16301Combined treatment for locally advanced cholangiocellular liver cancer - the case reportA. N. Polyakov0Yu. I. Patyutko1A. Yu. Syskova2K. A. Romanova3I. S. Bazin4O. N. Sergeeva5E. R. Virshke6E. S. Makarov7E. Yu. Antonova8A. A. Kirshin9D. V. Podluzhnyi10N.N.Blokhin National Medical Research Center of OncologyN.N.Blokhin National Medical Research Center of OncologyN.N.Blokhin National Medical Research Center of Oncology; N.I.Pirogov Russian National Research Medical University (RNRMU)N.N.Blokhin National Medical Research Center of OncologyN.N.Blokhin National Medical Research Center of OncologyN.N.Blokhin National Medical Research Center of OncologyN.N.BLokhin National Medical Research Center of OncologyN.N.BLokhin National Medical Research Center of OncologyN.N.Blokhin National Medical Research Center of Oncology; I.M.Sechenov First Moscow State Medical University (Sechenov University)S.G.Primushko Republican clinical Oncology dispensaryN.N.Blokhin National Medical Research Center of OncologyLiver resection is the standard in the treatment of patients with the local uncomplicated intrahepatic bile duct cancer. Systemic chemotherapy is prescribed in the presence of distant metastases. Difficulties in a choice of the treatment method come up when one or several factors are revealed: the tumor spread towards the surrounding structures, multiple liver lesions, lymph nodes involvement signs. The complications presence manages treatment strategy too. The case describes the possibilities of an individual multimodal approach in a treatment strategy for the patient with locally advanced liver cholangiocarcinoma complicated by obstructive jaundice, cholangitis, cholangiogenic abscesses. The surgical approach was approved as the main one. Methods of interventional radiology, chemotherapy, radiation therapy were applied when necessary. The mentioned above treatment strategy allowed us to achieve good results in this difficult clinical case. The patient is alive for more than four years from the time of surgery, signs of progression are not currently defined.https://www.rpmj.ru/rpmj/article/view/470intrahepatic bile duct cancercombined treatmentextensive liver resectionbile ducts resectioninterventional biliodigestive anastomosispostoperative chemotherapyintraductal radiotherapy
spellingShingle A. N. Polyakov
Yu. I. Patyutko
A. Yu. Syskova
K. A. Romanova
I. S. Bazin
O. N. Sergeeva
E. R. Virshke
E. S. Makarov
E. Yu. Antonova
A. A. Kirshin
D. V. Podluzhnyi
Combined treatment for locally advanced cholangiocellular liver cancer - the case report
Исследования и практика в медицине
intrahepatic bile duct cancer
combined treatment
extensive liver resection
bile ducts resection
interventional biliodigestive anastomosis
postoperative chemotherapy
intraductal radiotherapy
title Combined treatment for locally advanced cholangiocellular liver cancer - the case report
title_full Combined treatment for locally advanced cholangiocellular liver cancer - the case report
title_fullStr Combined treatment for locally advanced cholangiocellular liver cancer - the case report
title_full_unstemmed Combined treatment for locally advanced cholangiocellular liver cancer - the case report
title_short Combined treatment for locally advanced cholangiocellular liver cancer - the case report
title_sort combined treatment for locally advanced cholangiocellular liver cancer the case report
topic intrahepatic bile duct cancer
combined treatment
extensive liver resection
bile ducts resection
interventional biliodigestive anastomosis
postoperative chemotherapy
intraductal radiotherapy
url https://www.rpmj.ru/rpmj/article/view/470
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