Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis
Background: Host modulation therapy has emerged as a new concept for the treatment of periodontal disease. Recently, a lot of research is being done in product containing docosahexaenoic acid (DHA) and eicosapentanoic acid (EPA). Omega-3 PUFA have therapeutic, anti-inflammatory and protective proper...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426821001214 |
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| author | Debopriya Chatterjee Aishwarya Chatterjee Dheeraj Kalra Anjali Kapoor Sharmistha Vijay Saurabh Jain |
| author_facet | Debopriya Chatterjee Aishwarya Chatterjee Dheeraj Kalra Anjali Kapoor Sharmistha Vijay Saurabh Jain |
| author_sort | Debopriya Chatterjee |
| collection | DOAJ |
| description | Background: Host modulation therapy has emerged as a new concept for the treatment of periodontal disease. Recently, a lot of research is being done in product containing docosahexaenoic acid (DHA) and eicosapentanoic acid (EPA). Omega-3 PUFA have therapeutic, anti-inflammatory and protective properties. This systematic review analysed the adjunctive use of omega-3 fatty acids in periodontal therapy of periodontitis patients. Methods: PICO question (patient, intervention, comparison, and outcome) was formed. Keywords were generated and were fed in databases. The databases were Pubmed, Cochrane library and LIVIVO. Studies selected are Randomized clinical trial, clinical studies, and longitudinal studies. Meta –analysis were performed for Pocket depth (PD), Clinical attachment level (CAL), Gingival index (GI) and Plaque Index (PI). Risk of bias was also assessed. Results: On analysis of all the 8 studies at 3 months showed significant effect of omega −3 fatty acid on clinical attachment level (CAL), Pocket depth (PD). There was significant effect of omega-3 fatty acids in 4 studies at 6 months. Conclusion: Within the limitation of the review, omega- 3 polyunsaturated fatty acids seems to have a positive effect on periodontal healing following periodontal therapy. Chronic periodontitis patient should be counselled to incorporate omega −3 fatty acid in their diet along with standard periodontal therapy. |
| format | Article |
| id | doaj-art-8062b2f967e84b66a28dfe0793dce55c |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-8062b2f967e84b66a28dfe0793dce55c2024-11-23T06:28:59ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682022-01-011215562Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysisDebopriya Chatterjee0Aishwarya Chatterjee1Dheeraj Kalra2Anjali Kapoor3Sharmistha Vijay4Saurabh Jain5Department of Periodontics, RUHS-CDS, India; Corresponding author. 48 A Sahakar Nagar Jhotwara and Khatipura, Jaipur, 302012, India.Department of Prosthetic and Dental, State Cancer Institute, Jaipur, IndiaDepartment of Public Health Dentistry, YMT Dental College, Mumbai, IndiaDepartment of Periodontics, RUHS-CDS, IndiaDepartment of Periodontics, RUHS-CDS, IndiaMedical Officer (Dental), CHC, Nawacity, IndiaBackground: Host modulation therapy has emerged as a new concept for the treatment of periodontal disease. Recently, a lot of research is being done in product containing docosahexaenoic acid (DHA) and eicosapentanoic acid (EPA). Omega-3 PUFA have therapeutic, anti-inflammatory and protective properties. This systematic review analysed the adjunctive use of omega-3 fatty acids in periodontal therapy of periodontitis patients. Methods: PICO question (patient, intervention, comparison, and outcome) was formed. Keywords were generated and were fed in databases. The databases were Pubmed, Cochrane library and LIVIVO. Studies selected are Randomized clinical trial, clinical studies, and longitudinal studies. Meta –analysis were performed for Pocket depth (PD), Clinical attachment level (CAL), Gingival index (GI) and Plaque Index (PI). Risk of bias was also assessed. Results: On analysis of all the 8 studies at 3 months showed significant effect of omega −3 fatty acid on clinical attachment level (CAL), Pocket depth (PD). There was significant effect of omega-3 fatty acids in 4 studies at 6 months. Conclusion: Within the limitation of the review, omega- 3 polyunsaturated fatty acids seems to have a positive effect on periodontal healing following periodontal therapy. Chronic periodontitis patient should be counselled to incorporate omega −3 fatty acid in their diet along with standard periodontal therapy.http://www.sciencedirect.com/science/article/pii/S2212426821001214Periodontitisomega3 fatty acidsClinical attachment level |
| spellingShingle | Debopriya Chatterjee Aishwarya Chatterjee Dheeraj Kalra Anjali Kapoor Sharmistha Vijay Saurabh Jain Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis Journal of Oral Biology and Craniofacial Research Periodontitis omega3 fatty acids Clinical attachment level |
| title | Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis |
| title_full | Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis |
| title_fullStr | Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis |
| title_full_unstemmed | Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis |
| title_short | Role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis. A systematic review and meta-analysis |
| title_sort | role of adjunct use of omega 3 fatty acids in periodontal therapy of periodontitis a systematic review and meta analysis |
| topic | Periodontitis omega3 fatty acids Clinical attachment level |
| url | http://www.sciencedirect.com/science/article/pii/S2212426821001214 |
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