Preparation and Characterization of PEG4000 Palmitate/PEG8000 Palmitate-Solid Dispersion Containing the Poorly Water-Soluble Drug Andrographolide

Preparation and Characterization of PEG4000 Palmitate/PEG8000 Palmitate-Solid Dispersion Containing the Poorly Water-Soluble Drug Andrographolide

Solid dispersion (SD) is the effective approach to improve the dissolution rate and bioavailability of class II drugs with low water solubility and high tissue permeability in the Biopharmaceutics Classification System. This study investigated the effects of polyethylene glycol (PEG) molecular weigh...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qingyun Zeng, Liquan Ou, Guowei Zhao, Ping Cai, Zhenggen Liao, Wei Dong, Xinli Liang
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Advances in Polymer Technology
Online Access:	http://dx.doi.org/10.1155/2020/4239207
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Modification of Chitosan/PEG4000 dispersed with Lithium Triflate (LiCF\(_3\)SO\(_3\)) as a solid polymer electrolyte for the secondary battery
by: Kartika Sari, et al.
Published: (2024-12-01)

Insights into the formulation properties, biocompatibility, and permeability of poorly water-soluble methoxyflavones with PEG400 and propylene glycol
by: Eze Fredrick Nwude, et al.
Published: (2023-09-01)

Retinol and Retinyl Palmitate in Foetal Lung Mice: Sexual Dimorphism
by: Olga Carvalho, et al.
Published: (2013-01-01)

Regulation and Function of the Peg3 Imprinted Domain
by: Hongzhi He, et al.
Published: (2014-09-01)

Outcomes of percutaneous endoscopic gastrostomy (PEG) in HIV patients
by: Nikhitha Mantri, et al.
Published: (2024-12-01)

Lipase-Catalyzed Synthesis of Cetyl Palmitate in the Presence of n-Hexane and Ethyl Ether
by: Gustavo Gealh, et al.
Published: (2024-01-01)

Lupeol Attenuates Palmitate-Induced Hypertrophy in 3T3-L1 Adipocytes
by: Vaithinathan Selvaraju, et al.
Published: (2025-01-01)

Antiaging Property and Mechanism of Phase-Change Asphalt with PEG as an Additive
by: Huiru Wang, et al.
Published: (2020-01-01)

Impedance Spectroscopy and FTIR Studies of PEG - Based Polymer Electrolytes
by: Anji Reddy Polu, et al.
Published: (2011-01-01)

PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia
by: Tinatini Tchatchiashvili, et al.
Published: (2024-12-01)

Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet
by: Lakshmi Arivazhagan, et al.
Published: (2025-02-01)

Projecting the Potential Budget Impact Analysis of Paliperidone Palmitate in Egyptian Adult Patients with Schizophrenia
by: Gihan Elsisi, et al.
Published: (2023-08-01)

A Randomized Controlled Trial Evaluating a Low-Volume PEG Solution Plus Ascorbic Acid versus Standard PEG Solution in Bowel Preparation for Colonoscopy
by: Masahiro Tajika, et al.
Published: (2015-01-01)

Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques
by: Hezha Abdullah Ali, et al.
Published: (2022-01-01)

Palmitic Acid Accelerates Endothelial Cell Injury and Cardiovascular Dysfunction via Palmitoylation of PKM2
by: Yu He, et al.
Published: (2025-02-01)

RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function
by: Yunali Ashar, et al.
Published: (2022-08-01)

Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
by: Wen Yin, et al.
Published: (2025-01-01)

Quasi-cyclic extension based on PEG algorithm for construction of LDPC codes
by: LEI Jing1, et al.
Published: (2008-01-01)

Palmitic acid-induced cell death: impact of endoplasmic reticulum and oxidative stress, mitigated by L-citrulline
by: Md. Rezwanul Habib, et al.
Published: (2025-01-01)

Determination of Fatty Acid Metabolism with Dynamic [C]Palmitate Positron Emission Tomography of Mouse Heart In Vivo
by: Yinlin Li, et al.
Published: (2015-09-01)

Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
by: Junmei Tang, et al.
Published: (2016-01-01)

Le Paradoxe de la comédienne : Peg Woffington selon Charles Reade
by: Laurent Bury
Published: (2005-12-01)

Inhibition of Aβ Aggregation by Cholesterol-End-Modified PEG Vesicles and Micelles
by: Shota Watanabe, et al.
Published: (2024-12-01)

Reinforcement Learning-Based Sequential Control Policy for Multiple Peg-in-Hole Assembly
by: Xinyu Liu, et al.
Published: (2024-10-01)

Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes
by: Jiajing Yin, et al.
Published: (2015-01-01)

Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK
by: Naru Morita, et al.
Published: (2018-01-01)

A multidimensional assessment of adverse events associated with paliperidone palmitate: a real-world pharmacovigilance study using the FAERS and JADER databases
by: Siyu Lou, et al.
Published: (2025-01-01)

Study of PEG-rhG-CSF for the prevention of neutropenia in concurrent chemoradiotherapy for nasopharyngeal carcinoma
by: Lu Yang, et al.
Published: (2025-01-01)

Effect of Gamma Irradiation on Structural and Biological Properties of a PLGA-PEG-Hydroxyapatite Composite
by: Sima Shahabi, et al.
Published: (2014-01-01)

Interdisciplinary Management of Maxillary Canine Buccal Ectopia Associated with Peg Shaped Lateral Incisor
by: Karuna Singh Sawhny, et al.
Published: (2016-01-01)

Effect of MoS2 Yolk-Shell Nanostructure on the Thiophene Separation Performance of PEG Membrane
by: Ziman Hou, et al.
Published: (2022-01-01)

Polyethylene Glycol (PEG) Application Triggers Plant Dehydration but Does Not Accurately Simulate Drought
by: Gulnar Kylyshbayeva, et al.
Published: (2024-12-01)

Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis
by: Xiaojie Lin, et al.
Published: (2014-01-01)

Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4
by: Ming Zhang, et al.
Published: (2013-01-01)

Improving the Oxidation Stability and Shelf-Life of Peanut Oil by Addition of Rosemary Extract Combined with Vitamin C and Ascorbyl Palmitate
by: Ying Wang, et al.
Published: (2022-01-01)

Whole-Body Biodistribution, Dosimetry, and Metabolite Correction of [C]Palmitate: A PET Tracer for Imaging of Fatty Acid Metabolism
by: Nana L. Christensen MLS, et al.
Published: (2017-10-01)

Modulation of Dental Pulp Stem Cell Odontogenesis in a Tunable PEG-Fibrinogen Hydrogel System
by: Qiqi Lu, et al.
Published: (2015-01-01)

Improved Therapeutic Effect of Puerarin-Encapsulated PEG-PLGA Nanoparticle on an In Vitro Cerebral Infarction Model
by: Lei Li, et al.
Published: (2020-01-01)

The Role of pH in PEG-b-PAAc Modification of Gadolinium Oxide Nanostructures for Biomedical Applications
by: Eva Hemmer, et al.
Published: (2012-01-01)

Colostrum-Derived Melatonin Plus PEG Microspheres Modulate the Oxidative Metabolism of Human Colostrum Phagocytes
by: Caroline G. Silva, et al.
Published: (2025-01-01)