Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke
Ischemic stroke (IS) is a clinical syndrome in which limited or total brain dysfunction is caused by cerebrovascular lesions and lasts more than 24 hours or causes death. Ferroptosis, a regulatory form of cell death dominated by iron accumulation and lipid peroxidation, is thought to be involved in...
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| Format: | Article |
| Language: | zho |
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Editorial Office of New Medicine
2024-12-01
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| Series: | Yixue xinzhi zazhi |
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| Online Access: | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2412/HR5ZrkZ1tj5eChIaYufzeiI3aDOP6Q8AzIji66Ig.pdf |
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| _version_ | 1846100619294670848 |
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| author | PEI Xinyu WU Minmin ZHU Luwen |
| author_facet | PEI Xinyu WU Minmin ZHU Luwen |
| author_sort | PEI Xinyu |
| collection | DOAJ |
| description | Ischemic stroke (IS) is a clinical syndrome in which limited or total brain dysfunction is caused by cerebrovascular lesions and lasts more than 24 hours or causes death. Ferroptosis, a regulatory form of cell death dominated by iron accumulation and lipid peroxidation, is thought to be involved in the pathogenesis of IS. The occurrence of IS causes organ dysfunction. The effects on the gastrointestinal system lie mainly in the two-way communication between the intestine and the brain, involving the brain, gut microbiota and intestinal tissue, and it has been considered to be a key component of IS prognosis. This article takes ferroptosis as the main idea to discuss the research progress of the effect of gut microbiota on ferroptosis after IS, which provides a theoretical basis for the treatment and prevention of IS from the aspects of intestinal microbiota and ferroptosis mechanism. |
| format | Article |
| id | doaj-art-802ff3f7048847d69992f3e6dfa3d9a7 |
| institution | Kabale University |
| issn | 1004-5511 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of New Medicine |
| record_format | Article |
| series | Yixue xinzhi zazhi |
| spelling | doaj-art-802ff3f7048847d69992f3e6dfa3d9a72024-12-30T01:09:24ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112024-12-0134121408141610.12173/j.issn.1004-5511.2024100266576Research progress on the relationship between gut microbiota and ferroptosis after ischemic strokePEI XinyuWU MinminZHU LuwenIschemic stroke (IS) is a clinical syndrome in which limited or total brain dysfunction is caused by cerebrovascular lesions and lasts more than 24 hours or causes death. Ferroptosis, a regulatory form of cell death dominated by iron accumulation and lipid peroxidation, is thought to be involved in the pathogenesis of IS. The occurrence of IS causes organ dysfunction. The effects on the gastrointestinal system lie mainly in the two-way communication between the intestine and the brain, involving the brain, gut microbiota and intestinal tissue, and it has been considered to be a key component of IS prognosis. This article takes ferroptosis as the main idea to discuss the research progress of the effect of gut microbiota on ferroptosis after IS, which provides a theoretical basis for the treatment and prevention of IS from the aspects of intestinal microbiota and ferroptosis mechanism.https://yxxz.whuznhmedj.com/futureApi/storage/attach/2412/HR5ZrkZ1tj5eChIaYufzeiI3aDOP6Q8AzIji66Ig.pdfischemic strokegut microbiotaferroptosisapoplexy |
| spellingShingle | PEI Xinyu WU Minmin ZHU Luwen Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke Yixue xinzhi zazhi ischemic stroke gut microbiota ferroptosis apoplexy |
| title | Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| title_full | Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| title_fullStr | Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| title_full_unstemmed | Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| title_short | Research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| title_sort | research progress on the relationship between gut microbiota and ferroptosis after ischemic stroke |
| topic | ischemic stroke gut microbiota ferroptosis apoplexy |
| url | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2412/HR5ZrkZ1tj5eChIaYufzeiI3aDOP6Q8AzIji66Ig.pdf |
| work_keys_str_mv | AT peixinyu researchprogressontherelationshipbetweengutmicrobiotaandferroptosisafterischemicstroke AT wuminmin researchprogressontherelationshipbetweengutmicrobiotaandferroptosisafterischemicstroke AT zhuluwen researchprogressontherelationshipbetweengutmicrobiotaandferroptosisafterischemicstroke |