PARP1 inhibitors in breast cancer therapy. Mechanism of action and clinical use

PARP1 inhibitors in breast cancer therapy. Mechanism of action and clinical use

It is known that currently PARP inhibitors are actively used in the treatment of tumors of the female reproductive system. A large number of studies have been presented demonstrating the effectiveness of PARP inhibitors in the treatment of BRCA-associated ovarian cancer. It was found that mutations...

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Bibliographic Details
Main Authors: D. S. Dolgasheva, A. M. Pevzner, M. K. Ibragimova, N. V. Litvyakov, M. M. Tsyganov
Format: Article
Language:Russian
Published: ABV-press 2020-06-01
Series:Опухоли женской репродуктивной системы
Subjects:
breast cancer
parp1
inhibitors
chemotherapy
treatment effect
progression-free survival
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/703
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