Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice
Objective: To investigate the anti-fatigue properties in mice of water extracts from nine different types of medicinal and edible component compositions, including Polygonati Rhizoma, Laminariae Thallus, and Rubi Fructus. Methods: A group of 10 healthy KM mice, half female and half male, were random...
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The editorial department of Science and Technology of Food Industry
2025-01-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024010280 |
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| author | Yanxia CEN Yucai LIANG Jiangying ZENG Shenggao YIN Gailian ZHOU Shiman CHEN |
| author_facet | Yanxia CEN Yucai LIANG Jiangying ZENG Shenggao YIN Gailian ZHOU Shiman CHEN |
| author_sort | Yanxia CEN |
| collection | DOAJ |
| description | Objective: To investigate the anti-fatigue properties in mice of water extracts from nine different types of medicinal and edible component compositions, including Polygonati Rhizoma, Laminariae Thallus, and Rubi Fructus. Methods: A group of 10 healthy KM mice, half female and half male, were randomly assigned to each of the following groups: blank control (equal volume of distilled water), positive control (ginseng royal jelly oral liquid, 0.62 g/mL), and low, medium, and high (0.21, 0.62, 1.85 g/mL) dosage groups of water extract of compound Polygonati Rhizoma composition. The mice were gavaged continuously for 30 days and the weight data were collected during gavage. At the end of the experiment, the mice's strenuous swimming time, organ index, and serum urea nitrogen, liver, and muscle glycogen contents were examined. Results: The water extract of the compound Polygonati Rhizoma composition did not statistically differ from the blank control group in terms of the mice's weight (P>0.05), and no abnormalities were observed in the mice's organs (P>0.05). The water extract of compound Polygonati Rhizoma composition had the potential to greatly increase mouse endurance, extend their strenuous swimming time (P<0.05), lower the amount of urea nitrogen (P<0.01), and boost liver and muscle glycogen contents (P<0.01). Conclusion: Exercise tiredness is mitigated by the water extract of the compound Polygonati Rhizoma composition. |
| format | Article |
| id | doaj-art-7fed3875c40a4aa2946cd0470d20ee4d |
| institution | Kabale University |
| issn | 1002-0306 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
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| series | Shipin gongye ke-ji |
| spelling | doaj-art-7fed3875c40a4aa2946cd0470d20ee4d2025-01-10T06:49:31ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-01-0146234334810.13386/j.issn1002-0306.20240102802024010280-2Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on MiceYanxia CEN0Yucai LIANG1Jiangying ZENG2Shenggao YIN3Gailian ZHOU4Shiman CHEN5Guangxi University of Chinese Medicine, Nanning 530000, ChinaGuilin Mingshiwei Food Co., Ltd., Guilin 546600, ChinaGuilin Mingshiwei Food Co., Ltd., Guilin 546600, ChinaGuangxi University of Chinese Medicine, Nanning 530000, ChinaGuangxi University of Chinese Medicine, Nanning 530000, ChinaGuangxi University of Chinese Medicine, Nanning 530000, ChinaObjective: To investigate the anti-fatigue properties in mice of water extracts from nine different types of medicinal and edible component compositions, including Polygonati Rhizoma, Laminariae Thallus, and Rubi Fructus. Methods: A group of 10 healthy KM mice, half female and half male, were randomly assigned to each of the following groups: blank control (equal volume of distilled water), positive control (ginseng royal jelly oral liquid, 0.62 g/mL), and low, medium, and high (0.21, 0.62, 1.85 g/mL) dosage groups of water extract of compound Polygonati Rhizoma composition. The mice were gavaged continuously for 30 days and the weight data were collected during gavage. At the end of the experiment, the mice's strenuous swimming time, organ index, and serum urea nitrogen, liver, and muscle glycogen contents were examined. Results: The water extract of the compound Polygonati Rhizoma composition did not statistically differ from the blank control group in terms of the mice's weight (P>0.05), and no abnormalities were observed in the mice's organs (P>0.05). The water extract of compound Polygonati Rhizoma composition had the potential to greatly increase mouse endurance, extend their strenuous swimming time (P<0.05), lower the amount of urea nitrogen (P<0.01), and boost liver and muscle glycogen contents (P<0.01). Conclusion: Exercise tiredness is mitigated by the water extract of the compound Polygonati Rhizoma composition.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024010280medicinal and edible componentpolygonati rhizomaanti-fatiguestrenuous swimming timeserum urea nitrogenliver glycogenmuscle glycogen |
| spellingShingle | Yanxia CEN Yucai LIANG Jiangying ZENG Shenggao YIN Gailian ZHOU Shiman CHEN Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice Shipin gongye ke-ji medicinal and edible component polygonati rhizoma anti-fatigue strenuous swimming time serum urea nitrogen liver glycogen muscle glycogen |
| title | Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice |
| title_full | Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice |
| title_fullStr | Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice |
| title_full_unstemmed | Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice |
| title_short | Anti-fatigue Effect of Water Extract of Food as Medicine Compound Polygonati Rhizoma Composition on Mice |
| title_sort | anti fatigue effect of water extract of food as medicine compound polygonati rhizoma composition on mice |
| topic | medicinal and edible component polygonati rhizoma anti-fatigue strenuous swimming time serum urea nitrogen liver glycogen muscle glycogen |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024010280 |
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