Navigating the COVID-19 Therapeutic Landscape: Unveiling Novel Perspectives on FDA-Approved Medications, Vaccination Targets, and Emerging Novel Strategies

Navigating the COVID-19 Therapeutic Landscape: Unveiling Novel Perspectives on FDA-Approved Medications, Vaccination Targets, and Emerging Novel Strategies

Amidst the ongoing global challenge of the SARS-CoV-2 pandemic, the quest for effective antiviral medications remains paramount. This comprehensive review delves into the dynamic landscape of FDA-approved medications repurposed for COVID-19, categorized as antiviral and non-antiviral agents. Our foc...

Full description

Saved in:

Bibliographic Details
Main Authors:	Reham F. Barghash, Donato Gemmati, Ahmed M. Awad, Mustafa M. M. Elbakry, Veronica Tisato, Kareem Awad, Ajay Vikram Singh
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Molecules
Subjects:	molnupiravir SARS-CoV-2 drug repurposing vaccines variant of concerns (VOC) paxlovid
Online Access:	https://www.mdpi.com/1420-3049/29/23/5564
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Repurposing FDA-approved drugs targeting FZD10 in nasopharyngeal carcinoma: insights from molecular dynamics simulations and experimental validation
by: Chawalit Ngernsombat, et al.
Published: (2024-12-01)

Re-Evaluation and Retrospective Comparison of Serum Neutralization Induced by Three Different Types of Inactivated SARS-CoV-2 Vaccines
by: Weiyu Jiang, et al.
Published: (2024-10-01)

The Clinical Anatomy of SARS-CoV-2 Variants of Concern in Central Greece During October 2020–July 2022
by: Ioanna Voulgaridi, et al.
Published: (2024-12-01)

The First Case of Felty’s Syndrome Complicated by COVID-19 Infection
by: Li Y, et al.
Published: (2024-11-01)

Clinical real-world effectiveness of nirmatrelvir/ritonavir for the treatment of SARS-CoV-2 infection: A meta-analysis
by: Chienhsiu Huang, et al.
Published: (2024-09-01)

Garlic peel-based carbon quantum dots as a sustainable alternative for the sensitive and green spectrofluorometric quantification of molnupiravir in pharmaceutical capsules
by: Yomna A. Saber, et al.
Published: (2024-12-01)

COVID-19 newer and emerging treatment options
by: Suneetha Narreddy, et al.
Published: (2021-01-01)

Evaluating Drug Interaction Risks: Nirmatrelvir & Ritonavir Combination (PAXLOVID<sup>®</sup>) with Concomitant Medications in Real-World Clinical Settings
by: Petra Zatovkaňuková, et al.
Published: (2024-11-01)

Mitigating Paxlovid™-induced drug‒drug interaction toxicity: an in silico insight
by: Giang H. Ta, et al.
Published: (2024-11-01)

Early Versus Delayed Usage of Paxlovid in Severe Omicron‐Infected Patients With Hypoxemia: A Prospective Multiple‐Center Cohort Study
by: Yu‐Ji Wang, et al.
Published: (2024-11-01)

Comparison of the therapeutic effect of Paxlovid and Azvudine in the treatment of COVID-19: A retrospective study
by: Wei Yang, et al.
Published: (2024-12-01)

Acute kidney injury and tacrolimus toxicity in a kidney transplant recipient treated with nirmaltrevir/ritonavir: a case report
by: Jack Rycen, et al.
Published: (2024-12-01)

Identification of G-quadruplex-forming Sequences in Nucleocapsid Gene of SARS-CoV-2 Variants of Concern: An In Silico Analysis
by: Saeedeh Ghazaey Zidanloo
Published: (2024-02-01)

Validation study for assessing COVID-19 pneumonia treatments
by: Kaibin Lin, et al.
Published: (2024-11-01)

Long-COVID symptoms after multisystem inflammatory syndrome in children during different pandemic waves
by: Katarzyna Ptak, et al.
Published: (2024-10-01)

Coronavirus disease (COVID-19)-associated mucormycosis (CAM): The unholy triad of COVID-19, diabetes mellitus, and corticosteroid therapy
by: Deepak Juyal, et al.
Published: (2023-11-01)

Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Pregnant Women Treated with Nirmatrelvir/Ritonavir (Paxlovid) Using Salivary Polymerase Chain Reaction: A Prospective Cohort Study
by: Chun-Han Tseng, et al.
Published: (2024-12-01)

D-dimer for efficacy prediction in COVID-19 patients treated with paxlovid
by: Daishi Li, et al.
Published: (2024-11-01)

Experimental co-infection of calves with SARS-CoV-2 Delta and Omicron variants of concern
by: Konner Cool, et al.
Published: (2024-12-01)

RADx Variant Task Force Program for Assessing the Impact of Variants on SARS-CoV-2 Molecular and Antigen Tests
by: Richard Creager, et al.
Published: (2021-01-01)

Genotype-Structured Modeling of Variant Emergence and Its Impact on Virus Infection
by: Anass Bouchnita
Published: (2025-01-01)

Utilizing AI for the Identification and Validation of Novel Therapeutic Targets and Repurposed Drugs for Endometriosis
by: Bonnie Hei Man Liu, et al.
Published: (2025-02-01)

An allosteric inhibitor of Mycobacterium tuberculosis ArgJ: Implications to a novel combinatorial therapy
by: Archita Mishra, et al.
Published: (2018-02-01)

Volatile Organic Compounds and Carbonyls Pollution in Mexico City and an Urban Industrialized Area of Central Mexico
by: Elizabeth Vega, et al.
Published: (2022-04-01)

A Concise Review on Porous Adsorbents for Benzene and Other Volatile Organic Compounds
by: Jerzy Choma, et al.
Published: (2024-11-01)

Searching for novel MDM2/MDMX dual inhibitors through a drug repurposing approach
by: Keting Li, et al.
Published: (2024-12-01)

Unraveling the impact of SARS-CoV-2 mutations on immunity: insights from innate immune recognition to antibody and T cell responses
by: Rafael Bayarri-Olmos, et al.
Published: (2024-12-01)

A review of the immunogenicity and safety of booster doses of omicron variant-containing mRNA-1273 COVID-19 vaccines in adults and children
by: Frances Priddy, et al.
Published: (2024-12-01)

Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates
by: Panagiotis N. Lalagkas, et al.
Published: (2024-11-01)

Research and pilot analysis of bevacizumab repurposing potential and its impact in clinical practice
by: Antonio Ivanov, et al.
Published: (2024-12-01)

Associations between exposure to volatile organic compounds with obesity in adults
by: Runmiao Wu, et al.
Published: (2025-03-01)

A descriptive review on the real-world impact of Moderna, Inc. COVID-19 vaccines
by: Mary Bausch-Jurken, et al.
Published: (2024-12-01)

Effect of homologous or heterologous vaccine booster over two initial doses of inactivated COVID-19 vaccine
by: Viravarn Luvira, et al.
Published: (2024-12-01)

Going concern audit reporting in Bosnia and Herzegovina
by: Amira Pobrić
Published: (2024-01-01)

High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
by: Thomas J O'Brien, et al.
Published: (2025-01-01)

Genomic strategies for drug repurposing
by: Kirtan Dave, et al.
Published: (2024-11-01)

Targeting TCMR-associated cytokine genes for drug screening identifies PPARγ agonists as novel immunomodulatory agents in transplantation
by: Lu Hu, et al.
Published: (2025-01-01)

Identification of novel PAD2 inhibitors using pharmacophore-based virtual screening, molecular docking, and MD simulation studies
by: Prakash Jha, et al.
Published: (2024-11-01)

A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase
by: Swati Valmiki, et al.
Published: (2025-01-01)

Investigation of VOC Series Collected in a Refinery and Their Classification Based on Statistical Features
by: Alina Bărbulescu, et al.
Published: (2024-12-01)