The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study

The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study

Abstract Background Colorectal cancer (CRC) is a common gastrointestinal cancer, and even though oxaliplatin chemotherapy is effective, there is a high likelihood of relapse, indicating the presence of oxaliplatin-resistant CRC. Therefore, it is crucial to comprehend the molecular mechanisms of oxal...

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Bibliographic Details
Main Authors: Hoda Deli, Zeynab Vakili-Ghartavol, Yazdan Asgari, Gholamreza Tavoosidana, Ebrahim Eftekhar, Mohammad Hossein Ghahremani
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Colorectal cancer
MicroRNAs
Oxaliplatin
Chemotherapy resistance
Online Access:https://doi.org/10.1186/s12885-024-13392-2
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