The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran
Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran. Materials and Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. Antifungal sus...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2024-12-01
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| Series: | Iranian Journal of Microbiology |
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| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/4831 |
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| author | Zahra Rafat Davoud Roostaei Mohammadreza Mobayen Hamid Salehiniya Parimah Pournasrolah |
| author_facet | Zahra Rafat Davoud Roostaei Mohammadreza Mobayen Hamid Salehiniya Parimah Pournasrolah |
| author_sort | Zahra Rafat |
| collection | DOAJ |
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Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.
Materials and Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. Antifungal susceptibility testing was done by the CLSI M27-A4 document.
Results: Four blood samples were identified as positive. Candida parapsilosis complex (3 out of 4, 75%) was the predominant leading cause of candidemia. MIC values showed that all isolates were susceptible to itraconazole, amphotericin B, and 5-flucytosine.
Conclusion: It seems necessary to pay attention to Candida non-albicans species in antifungal therapy.
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| format | Article |
| id | doaj-art-7fb95292090940dba8ca2af3637fefb5 |
| institution | Kabale University |
| issn | 2008-3289 2008-4447 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj-art-7fb95292090940dba8ca2af3637fefb52025-01-06T08:38:42ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472024-12-0116610.18502/ijm.v16i6.17262The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern IranZahra Rafat0Davoud Roostaei1Mohammadreza Mobayen2Hamid Salehiniya3Parimah Pournasrolah4Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, IranDepartment of Pharmacology, School of Medicine, Guilan University of Medical Sciences, Rasht, IranBurn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, IranSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, IranStudent Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran. Materials and Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. Antifungal susceptibility testing was done by the CLSI M27-A4 document. Results: Four blood samples were identified as positive. Candida parapsilosis complex (3 out of 4, 75%) was the predominant leading cause of candidemia. MIC values showed that all isolates were susceptible to itraconazole, amphotericin B, and 5-flucytosine. Conclusion: It seems necessary to pay attention to Candida non-albicans species in antifungal therapy. https://ijm.tums.ac.ir/index.php/ijm/article/view/4831Candidemia;Burns;Epidemiology;Microbiology;Microbial sensitivity tests |
| spellingShingle | Zahra Rafat Davoud Roostaei Mohammadreza Mobayen Hamid Salehiniya Parimah Pournasrolah The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran Iranian Journal of Microbiology Candidemia; Burns; Epidemiology; Microbiology; Microbial sensitivity tests |
| title | The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran |
| title_full | The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran |
| title_fullStr | The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran |
| title_full_unstemmed | The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran |
| title_short | The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran |
| title_sort | microbiology epidemiology risk factors and clinical therapy of candidemia in burn patients hospitalized in velayat teaching hospital rasht northern iran |
| topic | Candidemia; Burns; Epidemiology; Microbiology; Microbial sensitivity tests |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/4831 |
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