The putative error prone polymerase REV1 mediates DNA damage and drug resistance in Candida albicans

Abstract Antimicrobial-induced DNA damage, and subsequent repair via upregulation of DNA repair factors, including error-prone translesion polymerases, can lead to the increased accumulation of mutations in the microbial genome, and ultimately increased risk of acquired mutations associated with ant...

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Bibliographic Details
Main Authors: Michelle R. Agyare-Tabbi, Deeva Uthayakumar, Desiree Francis, Laetitia Maroc, Chris Grant, Peter McQueen, Garret Westmacott, Hajer Shaker, Iwona Skulska, Isabelle Gagnon-Arsenault, Jonathan Boisvert, Christian R. Landry, Rebecca S. Shapiro
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-024-00057-0
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