Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism

Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism

Abstract Osteosarcoma (OS) is the most common primary malignant bone tumor. Recent evidence suggests that the novel long noncoding RNA DHRS4 antisense RNA 1 (DHRS4-AS1) serves an important role in cancer progression and metastasis. However, its function and molecular mechanism in OS remain largely u...

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Bibliographic Details
Main Authors: Zhouzhou Tang, Zhihao Li, Guofeng Wu, Jianjun Li, Jianye Tan, Lixin Zhu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Osteosarcoma
DHRS4-AS1
Long noncoding RNAs
MiR-362-5p
NPEPPS
Online Access:https://doi.org/10.1038/s41598-025-87246-7
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