Computational assessment of measurable residual disease in acute myeloid leukemia using mixture models

Computational assessment of measurable residual disease in acute myeloid leukemia using mixture models

Abstract Background The proportion of residual leukemic blasts after chemotherapy assessed by multiparameter flow cytometry, is an important prognostic factor for the risk of relapse and overall survival in acute myeloid leukemia (AML). This measurable residual disease (MRD) is used in clinical tria...

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Main Authors: Tim R. Mocking, Angèle Kelder, Tom Reuvekamp, Lok Lam Ngai, Philip Rutten, Patrycja Gradowska, Arjan A. van de Loosdrecht, Jacqueline Cloos, Costa Bachas
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00700-x
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