Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study)

Study protocol for a multicentre, 2×2 factorial, randomised, controlled trial evaluating the interest of intravenous iron and tranexamic acid to reduce blood transfusion in hip fracture patients (the HiFIT study)

Introduction Blood transfusion and anaemia are frequent and are associated with poor outcomes in patients with hip fracture (HF). We hypothesised that preoperative intravenous iron and tranexamic acid (TXA) may reduce the transfusion rate in these patients.Methods and analysis The HiFIT study is a m...

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Main Authors: Bertrand Drugeon, Olivier Mimoz, Karim Asehnoune, Antoine Roquilly, Sigismond Lasocki, Hélène Beloeil, Olivier Desebbe, Pierre Bouzat, Bruno Vielle, Thibault Loupec, Elsa Parot-Schinkel, Marc Danguy des Déserts, Maria Lahlou-Casulli, Vincent Collange, Alexis Duchalais, Delphine Garrigue, Benjamin Mounet, Franck Hamard, Jean-Stéphane David, Maxime Leger, Emmanuel Rineau, Guillaume Bouhours, Adeline Lebail, Emmanuel Samson, Xavier Capdevilla, Fabien Swisser, Marc Danguy Des Deserts, Sébastien Parent, Gaetan Gavazzi, Benjamin Bijok
Format: Article
Language:English
Published: BMJ Publishing Group 2021-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/1/e040273.full
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