Characterization of the T-cell receptor repertoire associated with lymph node metastasis in colorectal cancer

Characterization of the T-cell receptor repertoire associated with lymph node metastasis in colorectal cancer

PurposeColorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with lymph node (LN) metastasis playing a pivotal role in disease progression. This study aimed to explore the T-cell receptor (TCR) repertoire among CRC patients, distinguishing those with LN metastasis from th...

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Bibliographic Details
Main Authors: Ya’nan Zhen, Hong Wang, Runze Jiang, Fang Wang, Cunbao Chen, Zhongfa Xu, Ruixue Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
lymph node metastasis
T-cell receptor repertoire
TCR sequencing
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1354533/full
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