Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing

Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing

The treatment of tendon/ligament-to-bone injury is a long-standing research challenge in orthopedics and bone tissue engineering. Orderly healing of the fibrocartilage layer and mineralized bone layer is crucial for treating tendon-bone interface injuries. We designed a three-dimensional printed por...

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Bibliographic Details
Main Authors: Liwei Zhu, Yuzhe Liu, Yifu Sun, Zhenjia Che, Youbin Li, Tengyue Liu, Xudong Li, Chengzhe Yang, Lanfeng Huang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Materials Today Bio
Subjects:
Tendon/ligament-to-bone healing
Transforming growth factor-β3
Bioactive interface
Titanium scaffolds
Sustained-release system
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425001073
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