Cutting Through History: The Evolution of Glioblastoma Surgery

Despite significant advancements in neuro-oncology, management of glioblastoma remains a formidable challenge. Over the last century, the role and goals of surgery for patients with glioblastoma have evolved dramatically, with surgical intervention maintaining a central role in patient care. To unde...

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Main Authors: Abdullah H. Ishaque, Sunit Das
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/31/11/485
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author Abdullah H. Ishaque
Sunit Das
author_facet Abdullah H. Ishaque
Sunit Das
author_sort Abdullah H. Ishaque
collection DOAJ
description Despite significant advancements in neuro-oncology, management of glioblastoma remains a formidable challenge. Over the last century, the role and goals of surgery for patients with glioblastoma have evolved dramatically, with surgical intervention maintaining a central role in patient care. To understand the future role of surgery in the management of glioblastoma, we must review and appreciate the historical journey that has led us to this juncture. Here, we provide an overview of this evolution and speak about anticipated changes in the future. “<i>Certainly we cannot hope to solve the glioblastoma problem by throwing up our hands and saying there is nothing we can do. On the contrary, the solution lies in our constantly pressing on, making more and more strenuous efforts to remove these tumors, and not allowing ourselves to be deterred by any obstacles that lie in our path.</i>”—Ernest Sachs, 1950.
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spelling doaj-art-7ea8de08c83146b58c7dca8e1119400c2024-11-26T17:58:50ZengMDPI AGCurrent Oncology1198-00521718-77292024-10-0131116568657610.3390/curroncol31110485Cutting Through History: The Evolution of Glioblastoma SurgeryAbdullah H. Ishaque0Sunit Das1Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON M5S 1A1, CanadaDivision of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON M5S 1A1, CanadaDespite significant advancements in neuro-oncology, management of glioblastoma remains a formidable challenge. Over the last century, the role and goals of surgery for patients with glioblastoma have evolved dramatically, with surgical intervention maintaining a central role in patient care. To understand the future role of surgery in the management of glioblastoma, we must review and appreciate the historical journey that has led us to this juncture. Here, we provide an overview of this evolution and speak about anticipated changes in the future. “<i>Certainly we cannot hope to solve the glioblastoma problem by throwing up our hands and saying there is nothing we can do. On the contrary, the solution lies in our constantly pressing on, making more and more strenuous efforts to remove these tumors, and not allowing ourselves to be deterred by any obstacles that lie in our path.</i>”—Ernest Sachs, 1950.https://www.mdpi.com/1718-7729/31/11/485glioblastomasurgeryhistory
spellingShingle Abdullah H. Ishaque
Sunit Das
Cutting Through History: The Evolution of Glioblastoma Surgery
Current Oncology
glioblastoma
surgery
history
title Cutting Through History: The Evolution of Glioblastoma Surgery
title_full Cutting Through History: The Evolution of Glioblastoma Surgery
title_fullStr Cutting Through History: The Evolution of Glioblastoma Surgery
title_full_unstemmed Cutting Through History: The Evolution of Glioblastoma Surgery
title_short Cutting Through History: The Evolution of Glioblastoma Surgery
title_sort cutting through history the evolution of glioblastoma surgery
topic glioblastoma
surgery
history
url https://www.mdpi.com/1718-7729/31/11/485
work_keys_str_mv AT abdullahhishaque cuttingthroughhistorytheevolutionofglioblastomasurgery
AT sunitdas cuttingthroughhistorytheevolutionofglioblastomasurgery