Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound

Skeletal dysplasias form an assorted cluster of bone dysplasias that result in atypical and aberrant skeletal size and shape. The case discussed here was diagnosed as thanatophoric dysplasia during the second-trimester ultrasound examination and the medical termination of pregnancy was subsequently...

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Main Authors: Ranjit Singh Lahel, Sangeet Kumar, Rajesh Kumar Mishra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-11-01
Series:Journal of Medical Ultrasound
Subjects:
Online Access:https://journals.lww.com/10.4103/jmu.jmu_20_23
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author Ranjit Singh Lahel
Sangeet Kumar
Rajesh Kumar Mishra
author_facet Ranjit Singh Lahel
Sangeet Kumar
Rajesh Kumar Mishra
author_sort Ranjit Singh Lahel
collection DOAJ
description Skeletal dysplasias form an assorted cluster of bone dysplasias that result in atypical and aberrant skeletal size and shape. The case discussed here was diagnosed as thanatophoric dysplasia during the second-trimester ultrasound examination and the medical termination of pregnancy was subsequently done. The fetus had shortening of the limbs (micromelia) with long bones (shaped like a telephone receiver), a small conical thorax, a protuberant abdomen, increased skin thickness with a cloverleaf skull, and macrocephaly. The relevant details and review of literature pertinent to the case are hereby discussed.
format Article
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institution Kabale University
issn 0929-6441
2212-1552
language English
publishDate 2024-11-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Medical Ultrasound
spelling doaj-art-7e98b9aeb25243dba4e47ca7875ab1122024-12-09T09:44:24ZengWolters Kluwer Medknow PublicationsJournal of Medical Ultrasound0929-64412212-15522024-11-0132434134410.4103/jmu.jmu_20_23Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal UltrasoundRanjit Singh LahelSangeet KumarRajesh Kumar MishraSkeletal dysplasias form an assorted cluster of bone dysplasias that result in atypical and aberrant skeletal size and shape. The case discussed here was diagnosed as thanatophoric dysplasia during the second-trimester ultrasound examination and the medical termination of pregnancy was subsequently done. The fetus had shortening of the limbs (micromelia) with long bones (shaped like a telephone receiver), a small conical thorax, a protuberant abdomen, increased skin thickness with a cloverleaf skull, and macrocephaly. The relevant details and review of literature pertinent to the case are hereby discussed.https://journals.lww.com/10.4103/jmu.jmu_20_23cloverleaf skullmicromeliaprenatalthanatophoric dysplasiaultrasound
spellingShingle Ranjit Singh Lahel
Sangeet Kumar
Rajesh Kumar Mishra
Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
Journal of Medical Ultrasound
cloverleaf skull
micromelia
prenatal
thanatophoric dysplasia
ultrasound
title Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
title_full Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
title_fullStr Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
title_full_unstemmed Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
title_short Thanatophoric Dysplasia – Rare Fatal Skeletal Dysplasia Detected on Prenatal Ultrasound
title_sort thanatophoric dysplasia rare fatal skeletal dysplasia detected on prenatal ultrasound
topic cloverleaf skull
micromelia
prenatal
thanatophoric dysplasia
ultrasound
url https://journals.lww.com/10.4103/jmu.jmu_20_23
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AT sangeetkumar thanatophoricdysplasiararefatalskeletaldysplasiadetectedonprenatalultrasound
AT rajeshkumarmishra thanatophoricdysplasiararefatalskeletaldysplasiadetectedonprenatalultrasound