Novel strategies targeting mitochondria-lysosome contact sites for the treatment of neurological diseases

Novel strategies targeting mitochondria-lysosome contact sites for the treatment of neurological diseases

Mitochondria and lysosomes are critical for neuronal homeostasis, as highlighted by their dysfunction in various neurological diseases. Recent studies have identified dynamic membrane contact sites between mitochondria and lysosomes, independent of mitophagy and the lysosomal degradation of mitochon...

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Bibliographic Details
Main Authors:	Yinyin Xie, Wenlin Sun, Aoya Han, Xinru Zhou, Shijie Zhang, Changchang Shen, Yi Xie, Cui Wang, Nanchang Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	lysosomal dynamics mitochondria-lysosome contact sites mitochondrial network mitophagy neurological diseases substance exchanges
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1527013/full
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