Novel Epigallocatechin Gallate (EGCG) Analogs with Improved Biochemical Properties for Targeting Extracellular and Intracellular <i>Staphylococcus aureus</i>

Novel Epigallocatechin Gallate (EGCG) Analogs with Improved Biochemical Properties for Targeting Extracellular and Intracellular <i>Staphylococcus aureus</i>

<i>Staphylococcus aureus</i> is a leading cause of bloodstream infection (SAB), with up to 30% mortality. Despite treatment with standard antibiotics, one in three patients develops a persistent infection, which portends a five-fold increase in the risk of death. Persistent SAB has been...

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Bibliographic Details
Main Authors: Riley Grosso, Vy Nguyen, Syed Kaleem Ahmed, Annie Wong-Beringer
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Applied Microbiology
Subjects:
antibiotic resistance
antibiotic action
chemical modification
drug design
Gram-positive bacteria
host–pathogen interaction
Online Access:https://www.mdpi.com/2673-8007/4/4/107
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