Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease

Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease

IntroductionParkinson’s disease (PD) is a common neurodegenerative disorder primarily affecting motor function due to progressive loss of dopaminergic neurons in the substantia nigra. Current therapies offer symptomatic relief but fail to halt disease progression, highlighting the need for novel the...

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Bibliographic Details
Main Authors: Yong Hui Nies, Wei Ling Lim, Norwahidah Abd Karim, Mohamad Fairuz Yahaya, Seong Lin Teoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
neurodegenerative disease
neuroprotection
pesticide
dopaminergic neuron
mitochondrial function
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1478013/full
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