Amyotrophic lateral sclerosis diagnosis using machine learning and multi-omic data integration

Amyotrophic lateral sclerosis diagnosis using machine learning and multi-omic data integration

Amyotrophic Lateral Sclerosis (ALS) is a complex and rare neurodegenerative disorder characterized by significant genetic, molecular, and clinical heterogeneity. Despite numerous endeavors to discover the genetic factors underlying ALS, a significant number of these factors remain unknown. This know...

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Bibliographic Details
Main Authors: Hima Nikafshan Rad, Zheng Su, Anne Trinh, M.A. Hakim Newton, Jannah Shamsani, NYGC ALS Consortium, Abdul Karim, Abdul Sattar
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
ALS diagnosis
Pathway level analysis
Variational autoencoder
Multi-omic integration
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024146142
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