Effect of oral antihypertensive drugs on biochemical dosages in the elderly
Objective: to compare serum levels of uric acid, glucose, potassium and sodium in elderly users and non-users of oral antihypertensive drugs. Methods: observational, case-control study, including 232 elderly people with mean age 68.9 ± 7.4 years, of which 116 use and 116 do not use oral antihyperten...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidade Federal do Ceará
2016-12-01
|
| Series: | Rev Rene |
| Subjects: | |
| Online Access: | https://periodicos.ufc.br/rene/article/view/18850 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849233122233679872 |
|---|---|
| author | Maria Elizana Martins de Meneses Carvalho Eucário Leite Monteiro Alves Maria do Carmo de Carvalho e Martins |
| author_facet | Maria Elizana Martins de Meneses Carvalho Eucário Leite Monteiro Alves Maria do Carmo de Carvalho e Martins |
| author_sort | Maria Elizana Martins de Meneses Carvalho |
| collection | DOAJ |
| description | Objective: to compare serum levels of uric acid, glucose, potassium and sodium in elderly users and non-users of oral antihypertensive drugs. Methods: observational, case-control study, including 232 elderly people with mean age 68.9 ± 7.4 years, of which 116 use and 116 do not use oral antihypertensive drugs, of both genders, non-diabetic and with no renal disease. After venous blood collection, glucose and uric acid were measured by colorimetric method; and sodium and potassium by the ion-selective electrode method. Results: there was an association between use of antihypertensive drugs and elevations in serum uric acid levels (p=0.040). And, among the classes, diuretic drugs demonstrated in this study relation with changes in uric acid levels (p=0.02) when compared to the other classes. Conclusion: the use of antihypertensive drugs, especially diuretics, has been associated with an increase in serum uric acid levels in hypertensive users of oral antihypertensive drugs. |
| format | Article |
| id | doaj-art-7e2913d4d56b4531a75bf922cb69be61 |
| institution | Kabale University |
| issn | 1517-3852 2175-6783 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Universidade Federal do Ceará |
| record_format | Article |
| series | Rev Rene |
| spelling | doaj-art-7e2913d4d56b4531a75bf922cb69be612025-08-20T12:53:36ZengUniversidade Federal do CearáRev Rene1517-38522175-67832016-12-01176Effect of oral antihypertensive drugs on biochemical dosages in the elderlyMaria Elizana Martins de Meneses Carvalho0Eucário Leite Monteiro Alves1Maria do Carmo de Carvalho e Martins2Centro Universitário UninovafapiCentro Universitário UninovafapiCentro Universitário Uninovafapi e Universidade Federal do PiauíObjective: to compare serum levels of uric acid, glucose, potassium and sodium in elderly users and non-users of oral antihypertensive drugs. Methods: observational, case-control study, including 232 elderly people with mean age 68.9 ± 7.4 years, of which 116 use and 116 do not use oral antihypertensive drugs, of both genders, non-diabetic and with no renal disease. After venous blood collection, glucose and uric acid were measured by colorimetric method; and sodium and potassium by the ion-selective electrode method. Results: there was an association between use of antihypertensive drugs and elevations in serum uric acid levels (p=0.040). And, among the classes, diuretic drugs demonstrated in this study relation with changes in uric acid levels (p=0.02) when compared to the other classes. Conclusion: the use of antihypertensive drugs, especially diuretics, has been associated with an increase in serum uric acid levels in hypertensive users of oral antihypertensive drugs.https://periodicos.ufc.br/rene/article/view/18850AgedAntihypertensive AgentsDrug-Related Side Effects and Adverse Reactions. |
| spellingShingle | Maria Elizana Martins de Meneses Carvalho Eucário Leite Monteiro Alves Maria do Carmo de Carvalho e Martins Effect of oral antihypertensive drugs on biochemical dosages in the elderly Rev Rene Aged Antihypertensive Agents Drug-Related Side Effects and Adverse Reactions. |
| title | Effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| title_full | Effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| title_fullStr | Effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| title_full_unstemmed | Effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| title_short | Effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| title_sort | effect of oral antihypertensive drugs on biochemical dosages in the elderly |
| topic | Aged Antihypertensive Agents Drug-Related Side Effects and Adverse Reactions. |
| url | https://periodicos.ufc.br/rene/article/view/18850 |
| work_keys_str_mv | AT mariaelizanamartinsdemenesescarvalho effectoforalantihypertensivedrugsonbiochemicaldosagesintheelderly AT eucarioleitemonteiroalves effectoforalantihypertensivedrugsonbiochemicaldosagesintheelderly AT mariadocarmodecarvalhoemartins effectoforalantihypertensivedrugsonbiochemicaldosagesintheelderly |