An integrated cellular and sub-cellular model of cancer chemotherapy and therapies that target cell survival
Apoptosis resistance is a hallmark of human cancer, and tumor cells often become resistant due to defects in the programmed cell death machinery.Targeting key apoptosis regulators to overcome apoptotic resistance and promote rapid death of tumor cells is an exciting new strategy for cancer treatment...
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Main Authors: | Alexis B. Cook, Daniel R. Ziazadeh, Jianfeng Lu, Trachette L. Jackson |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1219 |
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