Downstream testing after CT coronary angiography: time for a rethink?

Objective We surveyed UK practice and compliance with the National Institute for Health and Care Excellence (NICE) ‘recent-onset chest pain’ guidance (Clinical Guideline 95, 2016) as a service quality initiative. We aimed to evaluate the diagnostic utility and efficacy of CT coronary angiography (CT...

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Main Authors: Matthias Schmitt, Michelle Claire Williams, Ben Holloway, Gareth Morgan-Hughes, Alice Veitch, Robin Van Lingen, Nicholas Bellenger
Format: Article
Language:English
Published: BMJ Publishing Group 2021-02-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/8/1/e001597.full
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author Matthias Schmitt
Michelle Claire Williams
Ben Holloway
Gareth Morgan-Hughes
Alice Veitch
Robin Van Lingen
Nicholas Bellenger
author_facet Matthias Schmitt
Michelle Claire Williams
Ben Holloway
Gareth Morgan-Hughes
Alice Veitch
Robin Van Lingen
Nicholas Bellenger
author_sort Matthias Schmitt
collection DOAJ
description Objective We surveyed UK practice and compliance with the National Institute for Health and Care Excellence (NICE) ‘recent-onset chest pain’ guidance (Clinical Guideline 95, 2016) as a service quality initiative. We aimed to evaluate the diagnostic utility and efficacy of CT coronary angiography (CTCA), NICE-guided investigation compliance, invasive coronary angiography (ICA) use and revascularisation.Methods A prospective analysis was conducted in nine UK centres between January 2018 and March 2020. The reporter decided whether the CTCA was diagnostic. Coronary artery disease was recorded with the Coronary Artery Disease–Reporting and Data System (CAD-RADS). Local electronic records and picture archiving/communication systems were used to collect data regarding functional testing, ICA and revascularisation. Duplication of coronary angiography without revascularisation was taken as a surrogate for ICA overuse.Results 5293 patients (mean age, 57±12 years; body mass index, 29±6 kg/m²; 50% men) underwent CTCA, with a 96% diagnostic scan rate. 618 (12%) underwent ICA, of which 48% (298/618) did not receive revascularisation. 3886 (73%) had CAD-RADS 0–2, with 1% (35/3886) undergoing ICA, of which 94% (33/35) received ICA as a second-line test. 547 (10%) had CAD-RADS 3, with 23% (125/547) undergoing ICA, of which 88% (110/125) chose ICA as a second-line test, with 26% (33/125) leading to revascularisation. For 552 (10%) CAD-RADS 4 and 91 (2%) CAD-RADS 5 patients, ICA revascularisation rates were 64% (221/345) and 74% (46/62), respectively.Conclusions While CTCA for recent-onset chest pain assessment has been shown to be a robust test, which negates the need for further investigation in three-quarters of patients, subsequent ICA overuse remains with almost half of these procedures not leading to revascularisation.
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spelling doaj-art-7d869ec4e52048a289301a3b835eb8122024-11-12T03:25:07ZengBMJ Publishing GroupOpen Heart2053-36242021-02-018110.1136/openhrt-2021-001597Downstream testing after CT coronary angiography: time for a rethink?Matthias Schmitt0Michelle Claire Williams1Ben Holloway2Gareth Morgan-Hughes3Alice Veitch4Robin Van Lingen5Nicholas Bellenger6Manchester University NHS Foundation Trust, Manchester, UKCentre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UKRadiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UKCardiology, University Hospitals Plymouth NHS Trust, Plymouth, UKRadiology, Salisbury NHS Foundation Trust, Salisbury, Wiltshire, UKRadiology, Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, UKCardiology, Royal Devon and Exeter Hospital, Exeter, UKObjective We surveyed UK practice and compliance with the National Institute for Health and Care Excellence (NICE) ‘recent-onset chest pain’ guidance (Clinical Guideline 95, 2016) as a service quality initiative. We aimed to evaluate the diagnostic utility and efficacy of CT coronary angiography (CTCA), NICE-guided investigation compliance, invasive coronary angiography (ICA) use and revascularisation.Methods A prospective analysis was conducted in nine UK centres between January 2018 and March 2020. The reporter decided whether the CTCA was diagnostic. Coronary artery disease was recorded with the Coronary Artery Disease–Reporting and Data System (CAD-RADS). Local electronic records and picture archiving/communication systems were used to collect data regarding functional testing, ICA and revascularisation. Duplication of coronary angiography without revascularisation was taken as a surrogate for ICA overuse.Results 5293 patients (mean age, 57±12 years; body mass index, 29±6 kg/m²; 50% men) underwent CTCA, with a 96% diagnostic scan rate. 618 (12%) underwent ICA, of which 48% (298/618) did not receive revascularisation. 3886 (73%) had CAD-RADS 0–2, with 1% (35/3886) undergoing ICA, of which 94% (33/35) received ICA as a second-line test. 547 (10%) had CAD-RADS 3, with 23% (125/547) undergoing ICA, of which 88% (110/125) chose ICA as a second-line test, with 26% (33/125) leading to revascularisation. For 552 (10%) CAD-RADS 4 and 91 (2%) CAD-RADS 5 patients, ICA revascularisation rates were 64% (221/345) and 74% (46/62), respectively.Conclusions While CTCA for recent-onset chest pain assessment has been shown to be a robust test, which negates the need for further investigation in three-quarters of patients, subsequent ICA overuse remains with almost half of these procedures not leading to revascularisation.https://openheart.bmj.com/content/8/1/e001597.full
spellingShingle Matthias Schmitt
Michelle Claire Williams
Ben Holloway
Gareth Morgan-Hughes
Alice Veitch
Robin Van Lingen
Nicholas Bellenger
Downstream testing after CT coronary angiography: time for a rethink?
Open Heart
title Downstream testing after CT coronary angiography: time for a rethink?
title_full Downstream testing after CT coronary angiography: time for a rethink?
title_fullStr Downstream testing after CT coronary angiography: time for a rethink?
title_full_unstemmed Downstream testing after CT coronary angiography: time for a rethink?
title_short Downstream testing after CT coronary angiography: time for a rethink?
title_sort downstream testing after ct coronary angiography time for a rethink
url https://openheart.bmj.com/content/8/1/e001597.full
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