Apremilast Cocrystals with Phenolic Coformers

Apremilast Cocrystals with Phenolic Coformers

Apremilast (APR) is an anti-inflammatory drug commonly used in the treatment of psoriasis. In efforts to enhance its solubility, several cocrystals with similar structural features have been developed. This study investigates the cocrystallization of APR with four phenolic-type coformers: phenol, ca...

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Bibliographic Details
Main Authors: Yelizaveta Naumkina, Bohumil Kratochvíl, Elena Korotkova, Jan Čejka
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
cocrystals
Apremilast
phenolic compounds
π–π interactions
hydrogen bonds
Online Access:https://www.mdpi.com/1420-3049/29/24/6060
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