Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review
To determine the outcome of full pulpotomy in management of mature permanent teeth with irreversible pulpitis when 2.5% versus other concentrations of sodium hypochlorite (NaOCl) were used to achieve haemostasis. Electronic searches were performed in PubMed, Embase, Web of Science, International Cli...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-11-01
|
| Series: | Indian Journal of Dental Research |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijdr.ijdr_979_22 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841553202934185984 |
|---|---|
| author | Aakriti Saini Amandeep Kaur Sidhartha Sharma Vijay Kumar Amrita Chawla Ajay Logani |
| author_facet | Aakriti Saini Amandeep Kaur Sidhartha Sharma Vijay Kumar Amrita Chawla Ajay Logani |
| author_sort | Aakriti Saini |
| collection | DOAJ |
| description | To determine the outcome of full pulpotomy in management of mature permanent teeth with irreversible pulpitis when 2.5% versus other concentrations of sodium hypochlorite (NaOCl) were used to achieve haemostasis. Electronic searches were performed in PubMed, Embase, Web of Science, International Clinical Trials Registry Platform, and ClinicalTrials.gov for English language articles until July 2021. Randomised clinical trials and cohort, cross-sectional, and case-control studies where full pulpotomy was performed to manage mature permanent molar teeth with irreversible pulpitis and no periapical radiolucency were included. Newcastle Ottawa Scale and the Cochrane risk of bias tool were used for quality assessment. The success rate for full pulpotomy was documented. The protocol was registered in PROSPERO database (CRD42020177214). Out of 861 studies, four were considered for data analysis. Three studies were single-arm prospective trials on pulpotomy, while one was a randomised control trial comparing pulpotomy and root canal treatment. A combined success rate of 93% from 117 teeth was reported from three studies using 2.5% NaOCl as a haemostatic agent. One study used 5% NaOCl and reported a success rate of 100% (n = 6 teeth). The certainty of evidence substantiated by the GRADE approach was of low quality. Overall quality assessment revealed a considerable risk of bias in three studies. Irrespective of the NaOCl concentration, the success rate of pulpotomy in mature permanent teeth with irreversible pulpitis was high. No study compared the different concentrations of NaOCl as a haemostatic agent. Further, randomised controlled trials are required to investigate the effect of NaOCl concentration for haemostasis on the outcome of pulpotomy. |
| format | Article |
| id | doaj-art-7d7c8e61b5974f83a3fac37613a46db6 |
| institution | Kabale University |
| issn | 0970-9290 1998-3603 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dental Research |
| spelling | doaj-art-7d7c8e61b5974f83a3fac37613a46db62025-01-09T11:28:09ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032024-11-0135333133810.4103/ijdr.ijdr_979_22Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic ReviewAakriti SainiAmandeep KaurSidhartha SharmaVijay KumarAmrita ChawlaAjay LoganiTo determine the outcome of full pulpotomy in management of mature permanent teeth with irreversible pulpitis when 2.5% versus other concentrations of sodium hypochlorite (NaOCl) were used to achieve haemostasis. Electronic searches were performed in PubMed, Embase, Web of Science, International Clinical Trials Registry Platform, and ClinicalTrials.gov for English language articles until July 2021. Randomised clinical trials and cohort, cross-sectional, and case-control studies where full pulpotomy was performed to manage mature permanent molar teeth with irreversible pulpitis and no periapical radiolucency were included. Newcastle Ottawa Scale and the Cochrane risk of bias tool were used for quality assessment. The success rate for full pulpotomy was documented. The protocol was registered in PROSPERO database (CRD42020177214). Out of 861 studies, four were considered for data analysis. Three studies were single-arm prospective trials on pulpotomy, while one was a randomised control trial comparing pulpotomy and root canal treatment. A combined success rate of 93% from 117 teeth was reported from three studies using 2.5% NaOCl as a haemostatic agent. One study used 5% NaOCl and reported a success rate of 100% (n = 6 teeth). The certainty of evidence substantiated by the GRADE approach was of low quality. Overall quality assessment revealed a considerable risk of bias in three studies. Irrespective of the NaOCl concentration, the success rate of pulpotomy in mature permanent teeth with irreversible pulpitis was high. No study compared the different concentrations of NaOCl as a haemostatic agent. Further, randomised controlled trials are required to investigate the effect of NaOCl concentration for haemostasis on the outcome of pulpotomy.https://journals.lww.com/10.4103/ijdr.ijdr_979_22full pulpotomyirreversible pulpitismineral trioxide aggregatesodium hypochloritetreatment outcome |
| spellingShingle | Aakriti Saini Amandeep Kaur Sidhartha Sharma Vijay Kumar Amrita Chawla Ajay Logani Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review Indian Journal of Dental Research full pulpotomy irreversible pulpitis mineral trioxide aggregate sodium hypochlorite treatment outcome |
| title | Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review |
| title_full | Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review |
| title_fullStr | Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review |
| title_full_unstemmed | Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review |
| title_short | Effect of Sodium Hypochlorite Concentration on the Outcome of Full Pulpotomy in Mature Permanent Teeth with Irreversible Pulpitis – A Systematic Review |
| title_sort | effect of sodium hypochlorite concentration on the outcome of full pulpotomy in mature permanent teeth with irreversible pulpitis a systematic review |
| topic | full pulpotomy irreversible pulpitis mineral trioxide aggregate sodium hypochlorite treatment outcome |
| url | https://journals.lww.com/10.4103/ijdr.ijdr_979_22 |
| work_keys_str_mv | AT aakritisaini effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview AT amandeepkaur effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview AT sidharthasharma effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview AT vijaykumar effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview AT amritachawla effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview AT ajaylogani effectofsodiumhypochloriteconcentrationontheoutcomeoffullpulpotomyinmaturepermanentteethwithirreversiblepulpitisasystematicreview |