Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration
This comprehensive review explores the multifaceted landscape of skin bioprinting, revolutionizing dermatological research. The applications of skin bioprinting utilizing techniques like extrusion-, droplet-, laser- and light-based methods, with specialized bioinks for skin biofabrication have been...
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| Format: | Article |
| Language: | English |
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IOP Publishing
2024-01-01
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| Series: | International Journal of Extreme Manufacturing |
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| Online Access: | https://doi.org/10.1088/2631-7990/ad878c |
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| author | I Deniz Derman Taino Rivera Laura Garriga Cerda Yogendra Pratap Singh Shweta Saini Hasan Erbil Abaci Ibrahim T Ozbolat |
| author_facet | I Deniz Derman Taino Rivera Laura Garriga Cerda Yogendra Pratap Singh Shweta Saini Hasan Erbil Abaci Ibrahim T Ozbolat |
| author_sort | I Deniz Derman |
| collection | DOAJ |
| description | This comprehensive review explores the multifaceted landscape of skin bioprinting, revolutionizing dermatological research. The applications of skin bioprinting utilizing techniques like extrusion-, droplet-, laser- and light-based methods, with specialized bioinks for skin biofabrication have been critically reviewed along with the intricate aspects of bioprinting hair follicles, sweat glands, and achieving skin pigmentation. Challenges remain with the need for vascularization, safety concerns, and the integration of automated processes for effective clinical translation. The review further investigates the incorporation of biosensor technologies, emphasizing their role in monitoring and enhancing the wound healing process. While highlighting the remarkable progress in the field, critical limitations and concerns are critically examined to provide a balanced perspective. This synthesis aims to guide scientists, engineers, and healthcare providers, fostering a deeper understanding of the current state, challenges, and future directions in skin bioprinting for transformative applications in tissue engineering and regenerative medicine. |
| format | Article |
| id | doaj-art-7d59b5c3c0b1414d8daf22b9de97ce25 |
| institution | Kabale University |
| issn | 2631-7990 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | International Journal of Extreme Manufacturing |
| spelling | doaj-art-7d59b5c3c0b1414d8daf22b9de97ce252024-11-19T12:15:15ZengIOP PublishingInternational Journal of Extreme Manufacturing2631-79902024-01-017101200910.1088/2631-7990/ad878cAdvancements in 3D skin bioprinting: processes, bioinks, applications and sensor integrationI Deniz Derman0https://orcid.org/0000-0001-9824-9071Taino Rivera1https://orcid.org/0009-0009-8650-5264Laura Garriga Cerda2https://orcid.org/0009-0002-4895-0497Yogendra Pratap Singh3https://orcid.org/0000-0003-4941-9323Shweta Saini4Hasan Erbil Abaci5https://orcid.org/0000-0002-4735-7790Ibrahim T Ozbolat6https://orcid.org/0000-0001-8328-4528Engineering Science and Mechanics Department, Penn State University , University Park, PA, United States of America; The Huck Institutes of the Life Sciences, Penn State University , University Park, PA, United States of AmericaBiomedical Engineering Department, Penn State University , University Park, PA, United States of AmericaDepartment of Dermatology, Columbia University Irving Medical Center , New York, NY, United States of AmericaEngineering Science and Mechanics Department, Penn State University , University Park, PA, United States of America; The Huck Institutes of the Life Sciences, Penn State University , University Park, PA, United States of AmericaThe Huck Institutes of the Life Sciences, Penn State University , University Park, PA, United States of AmericaDepartment of Dermatology, Columbia University Irving Medical Center , New York, NY, United States of America; Department of Biomedical Engineering, Columbia University , New York, NY, United States of AmericaEngineering Science and Mechanics Department, Penn State University , University Park, PA, United States of America; The Huck Institutes of the Life Sciences, Penn State University , University Park, PA, United States of America; Biomedical Engineering Department, Penn State University , University Park, PA, United States of America; Materials Research Institute, Penn State University , University Park, PA, United States of America; Cancer Institute, Penn State University , University Park, PA, United States of America; Neurosurgery Department, Penn State University , University Park, PA, United States of America; Department of Medical Oncology, Cukurova University , Adana, TurkeyThis comprehensive review explores the multifaceted landscape of skin bioprinting, revolutionizing dermatological research. The applications of skin bioprinting utilizing techniques like extrusion-, droplet-, laser- and light-based methods, with specialized bioinks for skin biofabrication have been critically reviewed along with the intricate aspects of bioprinting hair follicles, sweat glands, and achieving skin pigmentation. Challenges remain with the need for vascularization, safety concerns, and the integration of automated processes for effective clinical translation. The review further investigates the incorporation of biosensor technologies, emphasizing their role in monitoring and enhancing the wound healing process. While highlighting the remarkable progress in the field, critical limitations and concerns are critically examined to provide a balanced perspective. This synthesis aims to guide scientists, engineers, and healthcare providers, fostering a deeper understanding of the current state, challenges, and future directions in skin bioprinting for transformative applications in tissue engineering and regenerative medicine.https://doi.org/10.1088/2631-7990/ad878c3D bioprintingskin modelsskin tissue engineeringbiofabricationbiosensors |
| spellingShingle | I Deniz Derman Taino Rivera Laura Garriga Cerda Yogendra Pratap Singh Shweta Saini Hasan Erbil Abaci Ibrahim T Ozbolat Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration International Journal of Extreme Manufacturing 3D bioprinting skin models skin tissue engineering biofabrication biosensors |
| title | Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration |
| title_full | Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration |
| title_fullStr | Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration |
| title_full_unstemmed | Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration |
| title_short | Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration |
| title_sort | advancements in 3d skin bioprinting processes bioinks applications and sensor integration |
| topic | 3D bioprinting skin models skin tissue engineering biofabrication biosensors |
| url | https://doi.org/10.1088/2631-7990/ad878c |
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