Well-Characterized Polyethyleneimine-/Carboxylated-Polyethylene-Glycol-Functionalized Gold Nanoparticles as Prospective Nanoscale Control Materials for In Vitro Cell Viability Assays: Particle Characterization and Toxicity Tests in Eight Mammalian Cell Lines

Well-Characterized Polyethyleneimine-/Carboxylated-Polyethylene-Glycol-Functionalized Gold Nanoparticles as Prospective Nanoscale Control Materials for In Vitro Cell Viability Assays: Particle Characterization and Toxicity Tests in Eight Mammalian Cell Lines

The safety screening of manufactured nanomaterials (MNMs) is essential for their adoption by consumers and the marketplace. Lately, animal-based testing has been replaced by mechanistically informative in vitro assays due to the requirements of regulatory agencies. Cell viability assays are widely e...

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Bibliographic Details
Main Authors: Vytas Reipa, Vincent A. Hackley, Alessandro Tona, Min Beom Heo, Ye Ryeong Lee, Tae Geol Lee, Aaron Johnston-Peck, Tae Joon Cho
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Nanomaterials
Subjects:
gold nanoparticles
cell viability
assay controls
MTS
polyethylene imine
polyethylene glycol
Online Access:https://www.mdpi.com/2079-4991/15/2/79
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