Synthesis, biological evaluations, and in silico assessments of phenylamino quinazolinones as tyrosinase inhibitors
Abstract A series of novel phenylamino quinazolinone derivatives were designed and synthesized as potential tyrosinase inhibitors. Among these compounds, 9r emerged as the most potent derivative, exhibiting IC50 values of 17.02 ± 1.66 µM, compared to kojic acid as the positive control with an IC50 v...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-81328-8 |
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