Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial

Introduction Insomnia, a widespread sleep disorder, affects a significant portion of the global population. This study is the first in Asia to evaluate the efficacy of electrical vestibular stimulation (VeNS) as a treatment for insomnia in Hong Kong adults, addressing a gap in non-pharmacological in...

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Main Authors: Teris Cheung, Joyce Yuen Ting Lam, Kwan Hin Fong, Calvin Pak-Wing Cheng, Yu-Tao Xiang, Tim Man Ho Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Dialogues in Clinical Neuroscience
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Online Access:https://www.tandfonline.com/doi/10.1080/19585969.2025.2526547
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author Teris Cheung
Joyce Yuen Ting Lam
Kwan Hin Fong
Calvin Pak-Wing Cheng
Yu-Tao Xiang
Tim Man Ho Li
author_facet Teris Cheung
Joyce Yuen Ting Lam
Kwan Hin Fong
Calvin Pak-Wing Cheng
Yu-Tao Xiang
Tim Man Ho Li
author_sort Teris Cheung
collection DOAJ
description Introduction Insomnia, a widespread sleep disorder, affects a significant portion of the global population. This study is the first in Asia to evaluate the efficacy of electrical vestibular stimulation (VeNS) as a treatment for insomnia in Hong Kong adults, addressing a gap in non-pharmacological interventions.Methods A double-blind, randomized, sham-controlled trial was conducted with 101 adults exhibiting insomnia symptoms. Participants were randomized into active VeNS or sham groups (1:1 ratio) and underwent twenty 30-minute VeNS sessions over four weeks. Psychological outcomes, including insomnia severity, sleep quality, and quality of life were assessed at baseline (T1), post-intervention (T2). Follow-up assessments were conducted at one- (T3) and three-month (T4) to evaluate the sustainability of VeNS effects.Results Of 83 participants (40 VeNS and 43 sham-VeNS), the VeNS group showed significant reductions in insomnia severity at T2 (p = 0.03, d = -0.47) and T4 (p = 0.02, d = -0.32), alongside improved quality of life (i.e., role-physical) at T2.Conclusion VeNS is a novel, non-invasive and safe neuromodulation device that may serve as an adjunct treatment for primary insomnia. The present findings provide a foundation for future multisite comparison studies to further evaluate VeNS efficacy.Trial registration ClinicalTrials.gov Identifier: NCT04452981
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spelling doaj-art-7ce50b91cb7d40eea0ac19d38aabcd5b2025-08-20T03:50:25ZengTaylor & Francis GroupDialogues in Clinical Neuroscience1958-59692025-12-0127123624810.1080/19585969.2025.2526547Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trialTeris Cheung0Joyce Yuen Ting Lam1Kwan Hin Fong2Calvin Pak-Wing Cheng3Yu-Tao Xiang4Tim Man Ho Li5School of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, ChinaSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, ChinaSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, ChinaDepartment of Psychiatry, The University of Hong Kong, Hong Kong SAR, ChinaDepartment of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macau SAR, ChinaDepartment of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, ChinaIntroduction Insomnia, a widespread sleep disorder, affects a significant portion of the global population. This study is the first in Asia to evaluate the efficacy of electrical vestibular stimulation (VeNS) as a treatment for insomnia in Hong Kong adults, addressing a gap in non-pharmacological interventions.Methods A double-blind, randomized, sham-controlled trial was conducted with 101 adults exhibiting insomnia symptoms. Participants were randomized into active VeNS or sham groups (1:1 ratio) and underwent twenty 30-minute VeNS sessions over four weeks. Psychological outcomes, including insomnia severity, sleep quality, and quality of life were assessed at baseline (T1), post-intervention (T2). Follow-up assessments were conducted at one- (T3) and three-month (T4) to evaluate the sustainability of VeNS effects.Results Of 83 participants (40 VeNS and 43 sham-VeNS), the VeNS group showed significant reductions in insomnia severity at T2 (p = 0.03, d = -0.47) and T4 (p = 0.02, d = -0.32), alongside improved quality of life (i.e., role-physical) at T2.Conclusion VeNS is a novel, non-invasive and safe neuromodulation device that may serve as an adjunct treatment for primary insomnia. The present findings provide a foundation for future multisite comparison studies to further evaluate VeNS efficacy.Trial registration ClinicalTrials.gov Identifier: NCT04452981https://www.tandfonline.com/doi/10.1080/19585969.2025.2526547Vestibular stimulationinsomniarandomised clinical trialbrain stimulationefficacy
spellingShingle Teris Cheung
Joyce Yuen Ting Lam
Kwan Hin Fong
Calvin Pak-Wing Cheng
Yu-Tao Xiang
Tim Man Ho Li
Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
Dialogues in Clinical Neuroscience
Vestibular stimulation
insomnia
randomised clinical trial
brain stimulation
efficacy
title Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
title_full Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
title_fullStr Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
title_full_unstemmed Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
title_short Efficacy of electrical vestibular stimulation (VeNS) on adults with insomnia: A double-blind, randomized, sham-controlled trial
title_sort efficacy of electrical vestibular stimulation vens on adults with insomnia a double blind randomized sham controlled trial
topic Vestibular stimulation
insomnia
randomised clinical trial
brain stimulation
efficacy
url https://www.tandfonline.com/doi/10.1080/19585969.2025.2526547
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