Regulating Immune Responses Induced by PEGylated Messenger RNA–Lipid Nanoparticle Vaccine

Regulating Immune Responses Induced by PEGylated Messenger RNA–Lipid Nanoparticle Vaccine

Messenger RNA (mRNA)-based therapeutics have shown remarkable progress in the treatment and prevention of diseases. Lipid nanoparticles (LNPs) have shown great successes in delivering mRNAs. After an mRNA-LNP vaccine enters a cell via an endosome, mRNA is translated into an antigen, which can activa...

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Bibliographic Details
Main Authors: Hyein Jo, Jaewhoon Jeoung, Wonho Kim, Dooil Jeoung
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
ABC phenomenon
allergies
complement
immune tolerance
innate immunity
mRNA-LNPs
Online Access:https://www.mdpi.com/2076-393X/13/1/14
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