Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023)
Seoul orthohantavirus (SEOV) and pathogenic leptospires, two zoonotic agents causing similar symptoms in humans, were investigated in rat populations across several neighborhoods in Bamako, Mali. SEOV seroprevalence in brown rats (Rattus norvegicus) reached 14.8 %, while no infection was detected in...
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Elsevier
2025-06-01
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| Series: | One Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352771425001211 |
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| author | J. Garona A. Berard C. Tatard A. Kwasiborski P. Gauthier S. Ag Atteynine V. Hourdel A. Eusebe C. Diagne V. Caro C. Brouat N. Charbonnel V. Sauvage L. Granjon G. Castel |
| author_facet | J. Garona A. Berard C. Tatard A. Kwasiborski P. Gauthier S. Ag Atteynine V. Hourdel A. Eusebe C. Diagne V. Caro C. Brouat N. Charbonnel V. Sauvage L. Granjon G. Castel |
| author_sort | J. Garona |
| collection | DOAJ |
| description | Seoul orthohantavirus (SEOV) and pathogenic leptospires, two zoonotic agents causing similar symptoms in humans, were investigated in rat populations across several neighborhoods in Bamako, Mali. SEOV seroprevalence in brown rats (Rattus norvegicus) reached 14.8 %, while no infection was detected in black rats (Rattus rattus). Pathogenic leptospires were found in 8.7 % of brown rats, with significant inter-neighborhood variations, while only one black rat tested positive. Viral genetic analyses suggested that SEOV strains circulating in Bamako may result from a reassortment between two SEOV lineages. These findings highlight the widespread distribution of SEOV and the localized presence of pathogenic leptospires in Bamako, emphasizing the role of brown rats as reservoirs. These results can guide municipal authorities in implementing rodent control and prevention strategies to mitigate associated public health risks in Bamako. |
| format | Article |
| id | doaj-art-7c948a35ebd24a3e9cc1cc3e299b9c3f |
| institution | OA Journals |
| issn | 2352-7714 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | One Health |
| spelling | doaj-art-7c948a35ebd24a3e9cc1cc3e299b9c3f2025-08-20T02:36:02ZengElsevierOne Health2352-77142025-06-012010108510.1016/j.onehlt.2025.101085Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023)J. Garona0A. Berard1C. Tatard2A. Kwasiborski3P. Gauthier4S. Ag Atteynine5V. Hourdel6A. Eusebe7C. Diagne8V. Caro9C. Brouat10N. Charbonnel11V. Sauvage12L. Granjon13G. Castel14CBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceInstitut Pasteur, Université Paris Cité, Environment and Infectious Risks Unit, Laboratory for Urgent Response to Biological Threats (CIBU), Paris, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceInstitut d'Economie Rurale, IER, Bamako, MaliInstitut Pasteur, Université Paris Cité, Environment and Infectious Risks Unit, Laboratory for Urgent Response to Biological Threats (CIBU), Paris, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceInstitut Pasteur, Université Paris Cité, Environment and Infectious Risks Unit, Laboratory for Urgent Response to Biological Threats (CIBU), Paris, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceInstitut Pasteur, Université Paris Cité, Environment and Infectious Risks Unit, Centre National de Référence des Hantavirus, Paris, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, FranceCBGP, IRD, INRAE, CIRAD, Institut Agro, Univ Montpellier, Montpellier, France; Corresponding author.Seoul orthohantavirus (SEOV) and pathogenic leptospires, two zoonotic agents causing similar symptoms in humans, were investigated in rat populations across several neighborhoods in Bamako, Mali. SEOV seroprevalence in brown rats (Rattus norvegicus) reached 14.8 %, while no infection was detected in black rats (Rattus rattus). Pathogenic leptospires were found in 8.7 % of brown rats, with significant inter-neighborhood variations, while only one black rat tested positive. Viral genetic analyses suggested that SEOV strains circulating in Bamako may result from a reassortment between two SEOV lineages. These findings highlight the widespread distribution of SEOV and the localized presence of pathogenic leptospires in Bamako, emphasizing the role of brown rats as reservoirs. These results can guide municipal authorities in implementing rodent control and prevention strategies to mitigate associated public health risks in Bamako.http://www.sciencedirect.com/science/article/pii/S2352771425001211Seoul orthohantavirusLeptospiraRat-borne pathogensUrban ecosystem |
| spellingShingle | J. Garona A. Berard C. Tatard A. Kwasiborski P. Gauthier S. Ag Atteynine V. Hourdel A. Eusebe C. Diagne V. Caro C. Brouat N. Charbonnel V. Sauvage L. Granjon G. Castel Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) One Health Seoul orthohantavirus Leptospira Rat-borne pathogens Urban ecosystem |
| title | Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) |
| title_full | Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) |
| title_fullStr | Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) |
| title_full_unstemmed | Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) |
| title_short | Detection of two zoonotic pathogens, Seoul orthohantavirus and pathogenic Leptospira, in rats of Bamako, Mali (2021−2023) |
| title_sort | detection of two zoonotic pathogens seoul orthohantavirus and pathogenic leptospira in rats of bamako mali 2021 2023 |
| topic | Seoul orthohantavirus Leptospira Rat-borne pathogens Urban ecosystem |
| url | http://www.sciencedirect.com/science/article/pii/S2352771425001211 |
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