Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer

Background:. Patients who require surgical treatment for diabetic foot ulcer (DFU) or chronic limb-threatening ischemia (CLTI) are often in generally poor condition and have complications. General anesthesia may be risky in surgery for such patients. Thus, the authors perform surgery using periphera...

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Main Authors: Hideharu Nakamura, MD, PhD, Takaya Makiguchi, MD, PhD, Yumi Yamada, MD, Kei Sakurai, MD, Aya Tsunoda, MD, Nana Tomaru, MD, Ken Shirabe, MD, PhD, Satoshi Yokoo, DMD, DMSc
Format: Article
Language:English
Published: Wolters Kluwer 2024-11-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006333
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author Hideharu Nakamura, MD, PhD
Takaya Makiguchi, MD, PhD
Yumi Yamada, MD
Kei Sakurai, MD
Aya Tsunoda, MD
Nana Tomaru, MD
Ken Shirabe, MD, PhD
Satoshi Yokoo, DMD, DMSc
author_facet Hideharu Nakamura, MD, PhD
Takaya Makiguchi, MD, PhD
Yumi Yamada, MD
Kei Sakurai, MD
Aya Tsunoda, MD
Nana Tomaru, MD
Ken Shirabe, MD, PhD
Satoshi Yokoo, DMD, DMSc
author_sort Hideharu Nakamura, MD, PhD
collection DOAJ
description Background:. Patients who require surgical treatment for diabetic foot ulcer (DFU) or chronic limb-threatening ischemia (CLTI) are often in generally poor condition and have complications. General anesthesia may be risky in surgery for such patients. Thus, the authors perform surgery using peripheral nerve block under dexmedetomidine sedation for patients with DFU and CLTI. Methods:. This study evaluated intraoperative stress, anxiety, and safety in 18 patients undergoing peripheral nerve block with dexmedetomidine. Sedation levels were assessed using the observer’s assessment of alertness/sedation (OAA/S) score on a 5-point scale from 5 (awake) to 1 (deeply sedated). Postoperatively, a questionnaire was administered to assess intraoperative stress and memory. Intraoperative stress was assessed using a 6-point face scale (0 to 6: not at all to unbearably high), and intraoperative memory was rated on a 5-point numeric scale (1 to 5: no memory to everything). Results:. The intraoperative OAA/S score was 3–5, indicating that appropriate sedation was obtained. The mean intraoperative stress score was 0.72 (range: 0–3), and the mean intraoperative memory score was 2.44 (range: 1–4). One patient had bradycardia and 9 had hypoxemia. All of these cases were improved by decreasing the dose of dexmedetomidine and encouraging deep breathing on call. Conclusions:. These results suggest that this procedure is a useful method to reduce patient burden and alleviate stress and anxiety during surgery. However, dexmedetomidine may cause hypoxemia in patients with DFU or CLTI; thus, attention should be paid to hypoxemia and countermeasures should be taken against this adverse effect.
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spelling doaj-art-7c94397be9504c36b871259b827378ab2024-11-26T08:02:36ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742024-11-011211e633310.1097/GOX.0000000000006333202411000-00059Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot UlcerHideharu Nakamura, MD, PhD0Takaya Makiguchi, MD, PhD1Yumi Yamada, MD2Kei Sakurai, MD3Aya Tsunoda, MD4Nana Tomaru, MD5Ken Shirabe, MD, PhD6Satoshi Yokoo, DMD, DMSc7From the * Department of Plastic and Reconstructive Surgery, National Hospital Organization, Takasaki-shi, Japan† Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Maebashi-shi, JapanFrom the * Department of Plastic and Reconstructive Surgery, National Hospital Organization, Takasaki-shi, Japan† Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Maebashi-shi, JapanFrom the * Department of Plastic and Reconstructive Surgery, National Hospital Organization, Takasaki-shi, JapanFrom the * Department of Plastic and Reconstructive Surgery, National Hospital Organization, Takasaki-shi, Japan‡ Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi-shi, Japan.† Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Maebashi-shi, JapanBackground:. Patients who require surgical treatment for diabetic foot ulcer (DFU) or chronic limb-threatening ischemia (CLTI) are often in generally poor condition and have complications. General anesthesia may be risky in surgery for such patients. Thus, the authors perform surgery using peripheral nerve block under dexmedetomidine sedation for patients with DFU and CLTI. Methods:. This study evaluated intraoperative stress, anxiety, and safety in 18 patients undergoing peripheral nerve block with dexmedetomidine. Sedation levels were assessed using the observer’s assessment of alertness/sedation (OAA/S) score on a 5-point scale from 5 (awake) to 1 (deeply sedated). Postoperatively, a questionnaire was administered to assess intraoperative stress and memory. Intraoperative stress was assessed using a 6-point face scale (0 to 6: not at all to unbearably high), and intraoperative memory was rated on a 5-point numeric scale (1 to 5: no memory to everything). Results:. The intraoperative OAA/S score was 3–5, indicating that appropriate sedation was obtained. The mean intraoperative stress score was 0.72 (range: 0–3), and the mean intraoperative memory score was 2.44 (range: 1–4). One patient had bradycardia and 9 had hypoxemia. All of these cases were improved by decreasing the dose of dexmedetomidine and encouraging deep breathing on call. Conclusions:. These results suggest that this procedure is a useful method to reduce patient burden and alleviate stress and anxiety during surgery. However, dexmedetomidine may cause hypoxemia in patients with DFU or CLTI; thus, attention should be paid to hypoxemia and countermeasures should be taken against this adverse effect.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006333
spellingShingle Hideharu Nakamura, MD, PhD
Takaya Makiguchi, MD, PhD
Yumi Yamada, MD
Kei Sakurai, MD
Aya Tsunoda, MD
Nana Tomaru, MD
Ken Shirabe, MD, PhD
Satoshi Yokoo, DMD, DMSc
Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
Plastic and Reconstructive Surgery, Global Open
title Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
title_full Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
title_fullStr Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
title_full_unstemmed Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
title_short Surgery With Peripheral Nerve Block Under Dexmedetomidine Sedation for Foot Ulcer
title_sort surgery with peripheral nerve block under dexmedetomidine sedation for foot ulcer
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006333
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