Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer

Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer

Gallbladder cancer (GBC) is commonly diagnosed at late stages when conventional treatments achieve only modest clinical benefit. Therefore, effective treatments for advanced GBC are needed. In this context, the administration of T cells genetically engineered with chimeric antigen receptors (CAR) ha...

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Bibliographic Details
Main Authors: Ernesto Lopez, Sofía Hidalgo, Eduardo Roa, Javiera Gómez, Carlos Hermansen Truan, Evy Sanders, Cristian Carrasco, Rodrigo Pacheco, Flavio Salazar-Onfray, Manuel Varas-Godoy, Vincenzo Borgna, Alvaro Lladser
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Gallbladder cancer
Chimeric antigen receptor
CAR
Carcinoembryonic antigen
CEA
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2225291
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