Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC

Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC

Abstract SMAD3, a protein-coding gene, assumes a pivotal role within the transforming growth factor-beta (TGF-β) signaling pathway. Notably, aberrant SMAD3 expression has been linked to various malignancies. Nevertheless, an extensive examination of the comprehensive pan-cancer impact on SMAD3’s dia...

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Bibliographic Details
Main Authors: Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
smad3
Pan-cancer
TGF-β
LIHC
Diagnosis
Prognosis
Online Access:https://doi.org/10.1038/s41598-024-84553-3
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