Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties

Despite the global stabilization of the number of new HIV infections in recent years, there has been an increase in new infections among men who have sex with men. This fact indicates the lack of effectiveness of the measures and prevention campaigns established so far for this group. It is therefo...

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Main Authors: Santiago Moreno Guillen, María Jesús Vivancos Gallego, Matilde Sanchez Conde
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Farmacia Hospitalaria
Subjects:
Online Access:http://www.aulamedica.es/fh/pdf/10821.pdf
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author Santiago Moreno Guillen
María Jesús Vivancos Gallego
Matilde Sanchez Conde
author_facet Santiago Moreno Guillen
María Jesús Vivancos Gallego
Matilde Sanchez Conde
author_sort Santiago Moreno Guillen
collection DOAJ
description Despite the global stabilization of the number of new HIV infections in recent years, there has been an increase in new infections among men who have sex with men. This fact indicates the lack of effectiveness of the measures and prevention campaigns established so far for this group. It is therefore necessary to implement alternative preventive measures for them. Pre-exposure pharmacological prophylaxis (PrEP) is one of the best evaluated options and has had high protection rates in both clinical and real-life trials. The strategy has also shown an adequate profile in terms of safety, tolerance, adverse effects and cost-effectiveness in the studies carried out to assess this important topic.
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institution Kabale University
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spelling doaj-art-7c642b0f12404f898462b683d5c4a47a2024-12-02T04:55:26ZengElsevierFarmacia Hospitalaria1130-63432171-86952017-09-0141563063710.7399/fh.10821Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertaintiesSantiago Moreno Guillen0María Jesús Vivancos Gallego1Matilde Sanchez Conde2Infectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), Madrid. Department of Medicine, University of Alcalá de Henares, Madrid.Infectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), MadridInfectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), Madrid.Despite the global stabilization of the number of new HIV infections in recent years, there has been an increase in new infections among men who have sex with men. This fact indicates the lack of effectiveness of the measures and prevention campaigns established so far for this group. It is therefore necessary to implement alternative preventive measures for them. Pre-exposure pharmacological prophylaxis (PrEP) is one of the best evaluated options and has had high protection rates in both clinical and real-life trials. The strategy has also shown an adequate profile in terms of safety, tolerance, adverse effects and cost-effectiveness in the studies carried out to assess this important topic.http://www.aulamedica.es/fh/pdf/10821.pdfPre-exposure prophylaxisHIV infectionEfficacy
spellingShingle Santiago Moreno Guillen
María Jesús Vivancos Gallego
Matilde Sanchez Conde
Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
Farmacia Hospitalaria
Pre-exposure prophylaxis
HIV infection
Efficacy
title Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
title_full Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
title_fullStr Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
title_full_unstemmed Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
title_short Pre-exposure prophylaxis (PrEP) against HIV: efficacy, safety and uncertainties
title_sort pre exposure prophylaxis prep against hiv efficacy safety and uncertainties
topic Pre-exposure prophylaxis
HIV infection
Efficacy
url http://www.aulamedica.es/fh/pdf/10821.pdf
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