PRMT5-Mediated Arginine Methylation of ACSL4 Attenuates Its Stability and Suppresses Ferroptosis in Renal Cancer

Lipid-peroxidation-driven ferroptosis represents a vital mode of regulated cell death increasingly recognized for its role in cancer therapy. Lipid metabolism plays a crucial role in determining the vulnerability of cells to ferroptosis, particularly in cancer cells. The biosynthesis and remodeling...

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Bibliographic Details
Main Authors: Meng Zhang, Hao Liu, Rong Yin, Jiayu Xu, Siqi Fan, Xingyou Qian, Menghan Cao, Shu Li, Ao Zhang, Guodong Chen, Hongmei Yong, Zhongwei Li, Jin Bai
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0789
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