Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review

Both de Winter syndrome and Wellens syndrome mainly indicate severe stenosis in the proximal segment of the anterior descending coronary artery. However, as research deepens, the accuracy and specificity of diagnosing proximal left anterior descending coronary artery (LAD) culprit lesions separately...

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Main Authors: Fei Wang, Xuesong Zhang, Huihui Pang, Yuehai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1415306/full
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author Fei Wang
Xuesong Zhang
Huihui Pang
Yuehai Wang
author_facet Fei Wang
Xuesong Zhang
Huihui Pang
Yuehai Wang
author_sort Fei Wang
collection DOAJ
description Both de Winter syndrome and Wellens syndrome mainly indicate severe stenosis in the proximal segment of the anterior descending coronary artery. However, as research deepens, the accuracy and specificity of diagnosing proximal left anterior descending coronary artery (LAD) culprit lesions separately by de Winter syndrome or Wellens syndrome are challenged. The patient in this case developed both syndromes in a short period of time, and imaging showed significant stenosis of the proximal LAD, indicating a culprit lesion. The successive appearance of these two special electrocardiogram changes may increase the accuracy and specificity of diagnosing LAD as a culprit lesion, and the short-term occurrence of these two special electrocardiogram changes also suggests that the culprit lesion may be incomplete occlusion. In addition, de Winter syndrome is prone to missed diagnosis, while Wellens syndrome is prone to misdiagnosis or underestimation of its risk.
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publisher Frontiers Media S.A.
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series Frontiers in Cardiovascular Medicine
spelling doaj-art-7c31ba42784a49ddafe176a5353b52792025-01-09T06:10:09ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-01-011110.3389/fcvm.2024.14153061415306Evolution of de Winter syndrome to Wellens syndrome: a case report and literature reviewFei Wang0Xuesong Zhang1Huihui Pang2Yuehai Wang3Department of Cardiology, Shandong Corps Hospital of Chinese People’s Armed Police Forces, Jinan, Shandong, ChinaCardiology Department and Experimental Animal Center, Liaocheng People’s Hospital of Shandong University and Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng, Shandong, ChinaSchool of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, ChinaCardiology Department and Experimental Animal Center, Liaocheng People’s Hospital of Shandong University and Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng, Shandong, ChinaBoth de Winter syndrome and Wellens syndrome mainly indicate severe stenosis in the proximal segment of the anterior descending coronary artery. However, as research deepens, the accuracy and specificity of diagnosing proximal left anterior descending coronary artery (LAD) culprit lesions separately by de Winter syndrome or Wellens syndrome are challenged. The patient in this case developed both syndromes in a short period of time, and imaging showed significant stenosis of the proximal LAD, indicating a culprit lesion. The successive appearance of these two special electrocardiogram changes may increase the accuracy and specificity of diagnosing LAD as a culprit lesion, and the short-term occurrence of these two special electrocardiogram changes also suggests that the culprit lesion may be incomplete occlusion. In addition, de Winter syndrome is prone to missed diagnosis, while Wellens syndrome is prone to misdiagnosis or underestimation of its risk.https://www.frontiersin.org/articles/10.3389/fcvm.2024.1415306/fullde Winter syndromeWellens syndromeproximal LAD lesionculprit lesionspecificityincomplete occlusion
spellingShingle Fei Wang
Xuesong Zhang
Huihui Pang
Yuehai Wang
Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
Frontiers in Cardiovascular Medicine
de Winter syndrome
Wellens syndrome
proximal LAD lesion
culprit lesion
specificity
incomplete occlusion
title Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
title_full Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
title_fullStr Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
title_full_unstemmed Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
title_short Evolution of de Winter syndrome to Wellens syndrome: a case report and literature review
title_sort evolution of de winter syndrome to wellens syndrome a case report and literature review
topic de Winter syndrome
Wellens syndrome
proximal LAD lesion
culprit lesion
specificity
incomplete occlusion
url https://www.frontiersin.org/articles/10.3389/fcvm.2024.1415306/full
work_keys_str_mv AT feiwang evolutionofdewintersyndrometowellenssyndromeacasereportandliteraturereview
AT xuesongzhang evolutionofdewintersyndrometowellenssyndromeacasereportandliteraturereview
AT huihuipang evolutionofdewintersyndrometowellenssyndromeacasereportandliteraturereview
AT yuehaiwang evolutionofdewintersyndrometowellenssyndromeacasereportandliteraturereview