Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study
IntroductionAging-related deficits in the physiological properties of skeletal muscles limit the control of dynamic stability during walking. However, the specific causal relationships between these factors remain unclear. This study evaluated the effects of aging-related deficits in muscle properti...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1524751/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841543767049371648 |
|---|---|
| author | Shoma Kudo Masahiro Fujimoto Akinori Nagano |
| author_facet | Shoma Kudo Masahiro Fujimoto Akinori Nagano |
| author_sort | Shoma Kudo |
| collection | DOAJ |
| description | IntroductionAging-related deficits in the physiological properties of skeletal muscles limit the control of dynamic stability during walking. However, the specific causal relationships between these factors remain unclear. This study evaluated the effects of aging-related deficits in muscle properties on dynamic stability during walking.MethodsWalking movements were simulated using two-dimensional musculoskeletal models consisting of 18 Hill-type muscles. To assess the effects of aging-related deficits in muscle function on dynamic stability during walking, five models with different muscle properties were created, namely young adult (YA) and older adult (OA) models, models with reduced maximum isometric muscle force, reduced maximum muscle contraction velocity, and prolonged muscle deactivation time (∆F, ∆V, and ∆T models, respectively). The margin of stability (MoS) was used as a measure of dynamic stability during walking.Results and DiscussionThe MoS value of the OA model was greater than that of the YA model, and the ∆F model yielded a larger MoS value than those of the ∆V and ∆T models. Therefore, the OA model achieved a more dynamically stable state than the YA model and the ∆F model required a more stable state to sustain continuous walking compared to the ∆V and ∆T models. These findings indicate that aging-related deficits in muscle function limit the control of dynamic stability during walking with the degeneration of maximum isometric muscle force being the most influential factor. These findings could aid in the development of an intervention program to reduce the risk of falls in older adults effectively. |
| format | Article |
| id | doaj-art-7c24ded75baf440d8e14a5b787942286 |
| institution | Kabale University |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-7c24ded75baf440d8e14a5b7879422862025-01-13T06:10:48ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-01-011210.3389/fbioe.2024.15247511524751Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation studyShoma Kudo0Masahiro Fujimoto1Akinori Nagano2Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Kagawa, JapanHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Kagawa, JapanCollege of Sport and Health Science, Ritsumeikan University, Shiga, JapanIntroductionAging-related deficits in the physiological properties of skeletal muscles limit the control of dynamic stability during walking. However, the specific causal relationships between these factors remain unclear. This study evaluated the effects of aging-related deficits in muscle properties on dynamic stability during walking.MethodsWalking movements were simulated using two-dimensional musculoskeletal models consisting of 18 Hill-type muscles. To assess the effects of aging-related deficits in muscle function on dynamic stability during walking, five models with different muscle properties were created, namely young adult (YA) and older adult (OA) models, models with reduced maximum isometric muscle force, reduced maximum muscle contraction velocity, and prolonged muscle deactivation time (∆F, ∆V, and ∆T models, respectively). The margin of stability (MoS) was used as a measure of dynamic stability during walking.Results and DiscussionThe MoS value of the OA model was greater than that of the YA model, and the ∆F model yielded a larger MoS value than those of the ∆V and ∆T models. Therefore, the OA model achieved a more dynamically stable state than the YA model and the ∆F model required a more stable state to sustain continuous walking compared to the ∆V and ∆T models. These findings indicate that aging-related deficits in muscle function limit the control of dynamic stability during walking with the degeneration of maximum isometric muscle force being the most influential factor. These findings could aid in the development of an intervention program to reduce the risk of falls in older adults effectively.https://www.frontiersin.org/articles/10.3389/fbioe.2024.1524751/fullgait analysisbalance controlphysiological changesmargin of stability (MOS)fall preventionaging |
| spellingShingle | Shoma Kudo Masahiro Fujimoto Akinori Nagano Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study Frontiers in Bioengineering and Biotechnology gait analysis balance control physiological changes margin of stability (MOS) fall prevention aging |
| title | Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study |
| title_full | Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study |
| title_fullStr | Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study |
| title_full_unstemmed | Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study |
| title_short | Effects of aging-related muscle degeneration on dynamic stability during walking: a musculoskeletal computer simulation study |
| title_sort | effects of aging related muscle degeneration on dynamic stability during walking a musculoskeletal computer simulation study |
| topic | gait analysis balance control physiological changes margin of stability (MOS) fall prevention aging |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1524751/full |
| work_keys_str_mv | AT shomakudo effectsofagingrelatedmuscledegenerationondynamicstabilityduringwalkingamusculoskeletalcomputersimulationstudy AT masahirofujimoto effectsofagingrelatedmuscledegenerationondynamicstabilityduringwalkingamusculoskeletalcomputersimulationstudy AT akinorinagano effectsofagingrelatedmuscledegenerationondynamicstabilityduringwalkingamusculoskeletalcomputersimulationstudy |