Presumed gabapentin-induced myoclonus in two cats
Case series summary This case report describes the history and presentation of two cats with presumed gabapentin-induced myoclonus. Although this phenomenon is well documented in people, there are no previous reports in cats. Both cats in the current report had International Renal Interest Society (...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-11-01
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| Series: | Journal of Feline Medicine and Surgery Open Reports |
| Online Access: | https://doi.org/10.1177/20551169241273634 |
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| _version_ | 1846150469193302016 |
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| author | Caroline Buckley Croix Griffin Heather Anderson Sarah A Moore |
| author_facet | Caroline Buckley Croix Griffin Heather Anderson Sarah A Moore |
| author_sort | Caroline Buckley |
| collection | DOAJ |
| description | Case series summary This case report describes the history and presentation of two cats with presumed gabapentin-induced myoclonus. Although this phenomenon is well documented in people, there are no previous reports in cats. Both cats in the current report had International Renal Interest Society (IRIS) stage 2 chronic kidney disease, a history of seizures (one generalized, one focal), and received gabapentin before veterinary hospital visits to alleviate anxiety (doses in the range of 11.8–16.4 mg/kg). While in the hospital, both cats were noted to have intermittent short jerks of the head that were different from the seizure activity previously noted by their owners at home. These cases appear to be the first published reports of this potential adverse effect of gabapentin in cats and risk factors in the present cases mirror those described in people. Relevance and novel information Clinicians should be aware of the potential for this phenomenon in cats receiving recommended doses of gabapentin, and future studies should focus on the role of chronic kidney disease and other neurologic conditions as risk factors for development of this condition. |
| format | Article |
| id | doaj-art-7c13a3f1b3c740ae8cd6df7fba035e55 |
| institution | Kabale University |
| issn | 2055-1169 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Feline Medicine and Surgery Open Reports |
| spelling | doaj-art-7c13a3f1b3c740ae8cd6df7fba035e552024-11-28T17:04:05ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692024-11-011010.1177/20551169241273634Presumed gabapentin-induced myoclonus in two catsCaroline Buckley0Croix Griffin1Heather Anderson2Sarah A Moore3Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USADepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USADepartment of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, OH, USABluePearl Science, Tampa, FL, USACase series summary This case report describes the history and presentation of two cats with presumed gabapentin-induced myoclonus. Although this phenomenon is well documented in people, there are no previous reports in cats. Both cats in the current report had International Renal Interest Society (IRIS) stage 2 chronic kidney disease, a history of seizures (one generalized, one focal), and received gabapentin before veterinary hospital visits to alleviate anxiety (doses in the range of 11.8–16.4 mg/kg). While in the hospital, both cats were noted to have intermittent short jerks of the head that were different from the seizure activity previously noted by their owners at home. These cases appear to be the first published reports of this potential adverse effect of gabapentin in cats and risk factors in the present cases mirror those described in people. Relevance and novel information Clinicians should be aware of the potential for this phenomenon in cats receiving recommended doses of gabapentin, and future studies should focus on the role of chronic kidney disease and other neurologic conditions as risk factors for development of this condition.https://doi.org/10.1177/20551169241273634 |
| spellingShingle | Caroline Buckley Croix Griffin Heather Anderson Sarah A Moore Presumed gabapentin-induced myoclonus in two cats Journal of Feline Medicine and Surgery Open Reports |
| title | Presumed gabapentin-induced myoclonus in two cats |
| title_full | Presumed gabapentin-induced myoclonus in two cats |
| title_fullStr | Presumed gabapentin-induced myoclonus in two cats |
| title_full_unstemmed | Presumed gabapentin-induced myoclonus in two cats |
| title_short | Presumed gabapentin-induced myoclonus in two cats |
| title_sort | presumed gabapentin induced myoclonus in two cats |
| url | https://doi.org/10.1177/20551169241273634 |
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