The pivotal image findings of progressive multifocal leukoencephalopathy: A case report
Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients. A 60-year-old woman, who was on immunosuppressive therapy, presented with a sudden seizure and was diagnosed with PML based on magnetic res...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Tungs’ Medical Journal |
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| Online Access: | https://doi.org/10.4103/ETMJ.ETMJ-D-24-00020 |
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| author | Shou-De Ma Chih-Wei Wei Tai-Lin Huang Chao-Hsin Wu Shiang-Yu Chang |
| author_facet | Shou-De Ma Chih-Wei Wei Tai-Lin Huang Chao-Hsin Wu Shiang-Yu Chang |
| author_sort | Shou-De Ma |
| collection | DOAJ |
| description | Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients. A 60-year-old woman, who was on immunosuppressive therapy, presented with a sudden seizure and was diagnosed with PML based on magnetic resonance imaging (MRI) findings. Typically, PML appears on computed tomography scans as asymmetric focal zones of low attenuation in the periventricular and subcortical white matter, while MRI findings usually show multifocal demyelination in these areas. The imaging results in this case are consistent with the typical presentation of PML. |
| format | Article |
| id | doaj-art-7bf4e5510055436596e81797e5e77531 |
| institution | Kabale University |
| issn | 2071-3592 2949-9720 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tungs’ Medical Journal |
| spelling | doaj-art-7bf4e5510055436596e81797e5e775312025-01-17T10:57:17ZengWolters Kluwer Medknow PublicationsTungs’ Medical Journal2071-35922949-97202024-12-0118211411610.4103/ETMJ.ETMJ-D-24-00020The pivotal image findings of progressive multifocal leukoencephalopathy: A case reportShou-De MaChih-Wei WeiTai-Lin HuangChao-Hsin WuShiang-Yu ChangProgressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients. A 60-year-old woman, who was on immunosuppressive therapy, presented with a sudden seizure and was diagnosed with PML based on magnetic resonance imaging (MRI) findings. Typically, PML appears on computed tomography scans as asymmetric focal zones of low attenuation in the periventricular and subcortical white matter, while MRI findings usually show multifocal demyelination in these areas. The imaging results in this case are consistent with the typical presentation of PML.https://doi.org/10.4103/ETMJ.ETMJ-D-24-00020chronic kidney diseasecyclosporine aimmunocompromisedjc virusprogressive multifocal leukoencephalopathyseizure |
| spellingShingle | Shou-De Ma Chih-Wei Wei Tai-Lin Huang Chao-Hsin Wu Shiang-Yu Chang The pivotal image findings of progressive multifocal leukoencephalopathy: A case report Tungs’ Medical Journal chronic kidney disease cyclosporine a immunocompromised jc virus progressive multifocal leukoencephalopathy seizure |
| title | The pivotal image findings of progressive multifocal leukoencephalopathy: A case report |
| title_full | The pivotal image findings of progressive multifocal leukoencephalopathy: A case report |
| title_fullStr | The pivotal image findings of progressive multifocal leukoencephalopathy: A case report |
| title_full_unstemmed | The pivotal image findings of progressive multifocal leukoencephalopathy: A case report |
| title_short | The pivotal image findings of progressive multifocal leukoencephalopathy: A case report |
| title_sort | pivotal image findings of progressive multifocal leukoencephalopathy a case report |
| topic | chronic kidney disease cyclosporine a immunocompromised jc virus progressive multifocal leukoencephalopathy seizure |
| url | https://doi.org/10.4103/ETMJ.ETMJ-D-24-00020 |
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