Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure

<i>Background and Objectives</i>: The aim of this study was to assess any predisposing factors to the morbidity of fashioning and reversal of diverting ileostomy in a prospective cohort of patients who have undergone TME and low colo-rectal or colo-anal anastomosis for rectal cancer. <...

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Main Authors: Nikolaos Gouvas, Dimitrios Manatakis, Christos Agalianos, Nikoletta Dimitriou, Ioannis Baloyiannis, George Tzovaras, Evangelos Xynos
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/60/11/1864
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author Nikolaos Gouvas
Dimitrios Manatakis
Christos Agalianos
Nikoletta Dimitriou
Ioannis Baloyiannis
George Tzovaras
Evangelos Xynos
author_facet Nikolaos Gouvas
Dimitrios Manatakis
Christos Agalianos
Nikoletta Dimitriou
Ioannis Baloyiannis
George Tzovaras
Evangelos Xynos
author_sort Nikolaos Gouvas
collection DOAJ
description <i>Background and Objectives</i>: The aim of this study was to assess any predisposing factors to the morbidity of fashioning and reversal of diverting ileostomy in a prospective cohort of patients who have undergone TME and low colo-rectal or colo-anal anastomosis for rectal cancer. <i>Materials and Methods:</i> Consecutive patients with rectal cancer undergoing low anterior resection and a defunctioning loop ileostomy in three surgical units from 2016 to 2020 were included in the study and retrospectively analyzed. <i>Results</i>: One hundred eighty-two patients from three centres were included. Ileostomy-related mortality was 0.5%, attributed to renal failure.. Ileostomy-related morbidity was 46%. Postoperative ileus was seen in 37.4%, and dehydration in 18.8% of the patients. The readmission rate for ileostomy-related reasons was 15.4%. Stoma care was problematic in 15.7% or poor in 7% of the cases. Advanced age, male gender and obesity were independent risk factors for ileostomy-related morbidity. Ileostomy was reversed in 165 patients. The morbidity in 165 patients was 16%. Ileus was seen in 10.3%, anastomotic leak in 4.8% and wound infection in 12.7% of the cases. One patient died because of an anastomotic leak. No predisposing factors that affect the outcomes of ileostomy closure were identified. <i>Conclusions</i>: Diverting ileostomy-related morbidity is high. Life threatening dehydration and renal failure from ileus is more commonly seen in elderly, male and obese patients and should be anticipated. Ileostomy closure-related morbidity is low.
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spelling doaj-art-7b918f3a78d94a22b3e1fb769901fdf62024-11-26T18:12:43ZengMDPI AGMedicina1010-660X1648-91442024-11-016011186410.3390/medicina60111864Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and ClosureNikolaos Gouvas0Dimitrios Manatakis1Christos Agalianos2Nikoletta Dimitriou3Ioannis Baloyiannis4George Tzovaras5Evangelos Xynos6Department of General Surgery, Medical School, University of Cyprus, Nicosia 2404, CyprusDepartment of General Surgery, Naval & Veterans Hospital, 11521 Athens, GreeceDepartment of General Surgery, Naval & Veterans Hospital, 73200 Chania, GreeceDepartment of General Surgery, Medical School, University of Cyprus, Nicosia 2404, CyprusDepartment of General Surgery, University Hospital of Larissa, 41334 Larisa, GreeceDepartment of General Surgery, University Hospital of Larissa, 41334 Larisa, GreeceDepartment of General Surgery, Creta Interclinic Hospital, 71304 Heraklion, Greece<i>Background and Objectives</i>: The aim of this study was to assess any predisposing factors to the morbidity of fashioning and reversal of diverting ileostomy in a prospective cohort of patients who have undergone TME and low colo-rectal or colo-anal anastomosis for rectal cancer. <i>Materials and Methods:</i> Consecutive patients with rectal cancer undergoing low anterior resection and a defunctioning loop ileostomy in three surgical units from 2016 to 2020 were included in the study and retrospectively analyzed. <i>Results</i>: One hundred eighty-two patients from three centres were included. Ileostomy-related mortality was 0.5%, attributed to renal failure.. Ileostomy-related morbidity was 46%. Postoperative ileus was seen in 37.4%, and dehydration in 18.8% of the patients. The readmission rate for ileostomy-related reasons was 15.4%. Stoma care was problematic in 15.7% or poor in 7% of the cases. Advanced age, male gender and obesity were independent risk factors for ileostomy-related morbidity. Ileostomy was reversed in 165 patients. The morbidity in 165 patients was 16%. Ileus was seen in 10.3%, anastomotic leak in 4.8% and wound infection in 12.7% of the cases. One patient died because of an anastomotic leak. No predisposing factors that affect the outcomes of ileostomy closure were identified. <i>Conclusions</i>: Diverting ileostomy-related morbidity is high. Life threatening dehydration and renal failure from ileus is more commonly seen in elderly, male and obese patients and should be anticipated. Ileostomy closure-related morbidity is low.https://www.mdpi.com/1648-9144/60/11/1864defunctioning ileostomyrectal cancermorbidityileostomy reversal
spellingShingle Nikolaos Gouvas
Dimitrios Manatakis
Christos Agalianos
Nikoletta Dimitriou
Ioannis Baloyiannis
George Tzovaras
Evangelos Xynos
Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
Medicina
defunctioning ileostomy
rectal cancer
morbidity
ileostomy reversal
title Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
title_full Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
title_fullStr Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
title_full_unstemmed Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
title_short Defunctioning Ileostomy After Low Anterior Resection of Rectum: Morbidity Related to Fashioning and Closure
title_sort defunctioning ileostomy after low anterior resection of rectum morbidity related to fashioning and closure
topic defunctioning ileostomy
rectal cancer
morbidity
ileostomy reversal
url https://www.mdpi.com/1648-9144/60/11/1864
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