A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc

Introduction: Lumbar prolapsed intervertebral disc (PIVD) is a debilitating lower back condition, whose accurate and timely diagnosis is crucial for its effective management. Artificial intelligence (AI) and computer-aided diagnosis (CAD) techniques have the potential to revolutionise diagnosis by i...

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Main Authors: Sandeep Pattnaik, Manu Goyal, Rajneesh Kumar Gujral, Amit Mittal
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Neuroscience Informatics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772528625000366
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author Sandeep Pattnaik
Manu Goyal
Rajneesh Kumar Gujral
Amit Mittal
author_facet Sandeep Pattnaik
Manu Goyal
Rajneesh Kumar Gujral
Amit Mittal
author_sort Sandeep Pattnaik
collection DOAJ
description Introduction: Lumbar prolapsed intervertebral disc (PIVD) is a debilitating lower back condition, whose accurate and timely diagnosis is crucial for its effective management. Artificial intelligence (AI) and computer-aided diagnosis (CAD) techniques have the potential to revolutionise diagnosis by improving accuracy, efficiency, and objectivity. This systematic review with meta-analysis thus aims to thoroughly assess the available knowledge on the usability of different AI and CAD-based tools in lumbar PIVD diagnosis. Methods: A systematic search of electronic databases, between June and August 2024 for relevant full-text studies. The primary outcomes for review included the diagnostic accuracy (of each AI and CAD system. Subsequently, a meta-analysis was conducted to synthesise the results of the included studies. Result: A total of eight studies were identified, evaluating thirteen CAD or AI systems. The meta-analysis involved three of the studies, and it demonstrated a high pooled sensitivity (0.901, 95% CI: 0.871–0.924) and specificity (0.919, 95% CI: 0.898–0.936) for lumbar PIVD diagnosis. Conclusion: To conclude, these findings strongly support the potential of AI/CAD systems to improve the accuracy and efficiency of lumbar PIVD diagnosis. Prospero ID: CRD42023444785
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spelling doaj-art-7b6b920ddc5c444891e336704406bc5f2025-08-22T04:58:50ZengElsevierNeuroscience Informatics2772-52862025-09-015310022110.1016/j.neuri.2025.100221A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral discSandeep Pattnaik0Manu Goyal1Rajneesh Kumar Gujral2Amit Mittal3Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaMaharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaMaharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaMaharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, India; Corresponding author.Introduction: Lumbar prolapsed intervertebral disc (PIVD) is a debilitating lower back condition, whose accurate and timely diagnosis is crucial for its effective management. Artificial intelligence (AI) and computer-aided diagnosis (CAD) techniques have the potential to revolutionise diagnosis by improving accuracy, efficiency, and objectivity. This systematic review with meta-analysis thus aims to thoroughly assess the available knowledge on the usability of different AI and CAD-based tools in lumbar PIVD diagnosis. Methods: A systematic search of electronic databases, between June and August 2024 for relevant full-text studies. The primary outcomes for review included the diagnostic accuracy (of each AI and CAD system. Subsequently, a meta-analysis was conducted to synthesise the results of the included studies. Result: A total of eight studies were identified, evaluating thirteen CAD or AI systems. The meta-analysis involved three of the studies, and it demonstrated a high pooled sensitivity (0.901, 95% CI: 0.871–0.924) and specificity (0.919, 95% CI: 0.898–0.936) for lumbar PIVD diagnosis. Conclusion: To conclude, these findings strongly support the potential of AI/CAD systems to improve the accuracy and efficiency of lumbar PIVD diagnosis. Prospero ID: CRD42023444785http://www.sciencedirect.com/science/article/pii/S2772528625000366Artificial intelligenceDeep learningMachine learningMagnetic resonance imagingIntervertebral disc
spellingShingle Sandeep Pattnaik
Manu Goyal
Rajneesh Kumar Gujral
Amit Mittal
A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
Neuroscience Informatics
Artificial intelligence
Deep learning
Machine learning
Magnetic resonance imaging
Intervertebral disc
title A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
title_full A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
title_fullStr A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
title_full_unstemmed A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
title_short A systematic review and meta-analysis on the diagnostic accuracy of artificial intelligence and computer-aided diagnosis of lumbar prolapsed intervertebral disc
title_sort systematic review and meta analysis on the diagnostic accuracy of artificial intelligence and computer aided diagnosis of lumbar prolapsed intervertebral disc
topic Artificial intelligence
Deep learning
Machine learning
Magnetic resonance imaging
Intervertebral disc
url http://www.sciencedirect.com/science/article/pii/S2772528625000366
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