Valproic acid attenuates the severity of astrogliosis in the hippocampus of animal models of temporal lobe epilepsy

Reactive astrogliosis is one of the most frequency neuropathological alterations in the hippocampus of animal models and patients with temporal lobe epilepsy (TLE). Valproic acid (VPA), a widely used antiepileptic drug (AED), acts by blocking ion channels and enhancing GABAergic activity. This study...

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Bibliographic Details
Main Authors: Hu Feng, Jiamin Luo, Zhiwei Li, Yuxiao Zhao, Yamei Liu, Hongyan Zhu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:IBRO Neuroscience Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667242124000964
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