Ovarian estrogen deficiency participates in the pathogenesis of Alzheimer’s disease by regulating hippocampal mitochondrial function and extracellular matrix remodeling

Ovarian estrogen deficiency participates in the pathogenesis of Alzheimer’s disease by regulating hippocampal mitochondrial function and extracellular matrix remodeling

Objective‍　‍The incidence of Alzheimer's disease (AD) in postmenopausal women is significantly increased with ageing. Menopause induced ovarian estrogen deficiency has been regarded as one of the causative risk factor of AD, but currently the detail mechanisms underlying estrogen regulation on...

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Bibliographic Details
Main Authors: ZHANG Xuan, ZHOU Maohu, MENG Zhaoyou
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-08-01
Series:陆军军医大学学报
Subjects:
menopause
ovarian removal
hippocampus
multiomics analysis
alzheimer’s disease
Online Access:http://aammt.tmmu.edu.cn/html/202505076.html
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