Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum
Ancient schwannoma is a rare benign variant of schwannoma with marked degenerative changes, often mimicking malignancies, particularly when retroperitoneal and pararenal. A 34-year-old woman presented with a rapidly growing 15 cm retroperitoneal pararenal mass. Imaging suggested an aggressive malign...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442024002742 |
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| author | Neha Aggarwal Shaivy Malik Charanjeet Ahluwalia |
| author_facet | Neha Aggarwal Shaivy Malik Charanjeet Ahluwalia |
| author_sort | Neha Aggarwal |
| collection | DOAJ |
| description | Ancient schwannoma is a rare benign variant of schwannoma with marked degenerative changes, often mimicking malignancies, particularly when retroperitoneal and pararenal. A 34-year-old woman presented with a rapidly growing 15 cm retroperitoneal pararenal mass. Imaging suggested an aggressive malignancy. Surgical resection and histopathology revealed a well-encapsulated tumor with degenerative changes, nuclear atypia, and strong S100 positivity, confirming ancient schwannoma. Complete excision achieved negative margins, and follow-up showed no recurrence. Diagnostic challenges arise from its rarity and atypical features. Histopathology is crucial for differentiation from malignancies. Ancient schwannomas should be considered for large retroperitoneal masses to ensure accurate diagnosis and management. |
| format | Article |
| id | doaj-art-7a96a9bc327d49089784a54cd2391187 |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-7a96a9bc327d49089784a54cd23911872025-01-14T04:12:22ZengElsevierUrology Case Reports2214-44202025-01-0158102920Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrumNeha Aggarwal0Shaivy Malik1Charanjeet Ahluwalia2Department of Pathology, Vardhman Mahavir Medical College And Safdarjung Hospital, New Delhi, 110029, IndiaDepartment of Pathology, Vardhman Mahavir Medical College And Safdarjung Hospital, New Delhi, 110029, IndiaCorresponding author. Department of Pathology, Vardhman Mahavir Medical College And Safdarjung Hospital, Room No. 403, New Delhi, 110029, India.; Department of Pathology, Vardhman Mahavir Medical College And Safdarjung Hospital, New Delhi, 110029, IndiaAncient schwannoma is a rare benign variant of schwannoma with marked degenerative changes, often mimicking malignancies, particularly when retroperitoneal and pararenal. A 34-year-old woman presented with a rapidly growing 15 cm retroperitoneal pararenal mass. Imaging suggested an aggressive malignancy. Surgical resection and histopathology revealed a well-encapsulated tumor with degenerative changes, nuclear atypia, and strong S100 positivity, confirming ancient schwannoma. Complete excision achieved negative margins, and follow-up showed no recurrence. Diagnostic challenges arise from its rarity and atypical features. Histopathology is crucial for differentiation from malignancies. Ancient schwannomas should be considered for large retroperitoneal masses to ensure accurate diagnosis and management.http://www.sciencedirect.com/science/article/pii/S2214442024002742Ancient schwannomaPararenal massSurgical excisionNeoplasmMesenchymal malignancySchwannoma |
| spellingShingle | Neha Aggarwal Shaivy Malik Charanjeet Ahluwalia Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum Urology Case Reports Ancient schwannoma Pararenal mass Surgical excision Neoplasm Mesenchymal malignancy Schwannoma |
| title | Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum |
| title_full | Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum |
| title_fullStr | Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum |
| title_full_unstemmed | Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum |
| title_short | Gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy: A diagnostic conundrum |
| title_sort | gigantic retroperitoneal pararenal ancient schwannoma masquerading as a mesenchymal malignancy a diagnostic conundrum |
| topic | Ancient schwannoma Pararenal mass Surgical excision Neoplasm Mesenchymal malignancy Schwannoma |
| url | http://www.sciencedirect.com/science/article/pii/S2214442024002742 |
| work_keys_str_mv | AT nehaaggarwal giganticretroperitonealpararenalancientschwannomamasqueradingasamesenchymalmalignancyadiagnosticconundrum AT shaivymalik giganticretroperitonealpararenalancientschwannomamasqueradingasamesenchymalmalignancyadiagnosticconundrum AT charanjeetahluwalia giganticretroperitonealpararenalancientschwannomamasqueradingasamesenchymalmalignancyadiagnosticconundrum |