Development of a population of digital brain phantoms for radionuclide imaging research in Parkinson’s disease

Development of a population of digital brain phantoms for radionuclide imaging research in Parkinson’s disease

Abstract Purpose Dopamine transporter (DAT) SPECT is a powerful tool for early diagnosis of Parkinson’s disease (PD), while digital phantoms and Monte Carlo (MC) simulations can serve as important research tools. This study aims to develop a novel digital brain phantom population for 99mTc-TRODAT-1...

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Bibliographic Details
Main Authors: Wenbo Huang, Han Jiang, Guang-Uei Hung, Yonghua Zhao, Ruibing Wang, Greta S. P. Mok
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Physics
Subjects:
Parkinson’s disease
DAT SPECT
Phantom population
Monte Carlo simulation
Attenuation correction
Scatter correction.
Online Access:https://doi.org/10.1186/s40658-025-00787-8
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