Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool

Tauopathy is a spectrum of diseases characterized by fibrillary tau aggregate formation in neurons and glial cells in the brain. Tau aggregation originates in the brainstem and entorhinal cortex and then spreads throughout the brain in Alzheimer’s disease (AD), which is the most prevalent type of ta...

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Main Authors: Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai
Format: Article
Language:English
Published: The Biophysical Society of Japan 2024-12-01
Series:Biophysics and Physicobiology
Subjects:
tauopathy
alzheimer’s disease
cry2olig
Online Access:https://doi.org/10.2142/biophysico.bppb-v21.0023
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