Syringin as a novel therapeutic agent for renal cell carcinoma by targeting EGFR/PI3K/Akt pathway and enhancing sunitinib efficacy

Syringin as a novel therapeutic agent for renal cell carcinoma by targeting EGFR/PI3K/Akt pathway and enhancing sunitinib efficacy

Syringin, a natural bioactive compound extracted from Acanthopanax senticosus, has demonstrated potential therapeutic value in cancer treatment. However, its efficacy in treating renal cell carcinoma (RCC) remains unexplored. This study aims to investigate the therapeutic effects and underlying mech...

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Bibliographic Details
Main Authors:	Zixuan Chen, Sheng Cheng, An Xu, Chengtao Han, Xing Jia, Min Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	Journal of Functional Foods
Subjects:	Renal cell carcinoma Syringin Network pharmacology Sunitinib Resistance
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464624005589
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